Percorrer por autor Porto, G.

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6-Fev-2002Co-selection of the H63D mutation and the HLA-A29 allele: a new paradigm of linkage disequilibrium?Cardoso, C.; Alves, H.; Mascaranhas, M.; Gonçalves, R.; Oliveira, P.; Rodrigues, P.; Cruz, E.; Sousa, M.; Porto, G.articleopenAccess
Nov-2013Effects of highly conserved major histocompatibility complex (MHC) extended haplotypes on iron and low CD8+ T lymphocyte phenotypes in HFE C282Y homozygous hemochromatosis patients from three geographically distant areasCosta, M.; Cruz, E.; Barton, J.; Thorstensen, K.; Morais, S.; da Silva, B.; Pinto, J.; Vieira, C.; Vieira, J.; Acton, R.; Porto, G.articleopenAccess
Abr-2017Genetic disruption of NRF2 promotes the development of necroinflammation and liver fibrosis in a mouse model of HFE-hereditary hemochromatosisDuarte, T.; Caldas, C.; Santos, A.; Silva-Gomes, S.; Santos-Gonçalves, A.; Martins, M.; Porto, G.; Lopes, J.articleopenAccess
1-Set-2017Hepcidin is regulated by promoter-associated histone acetylation and HDAC3Pasricha, S.; Lim, P.; Duarte, T.; Casu, C.; Oosterhuis, D.; Mleczko-Sanecka, K.; Suciu, M.; Da Silva, A.; Al-Hourani, K.; Arezes, J.; McHugh, K.; Gooding, S.; Frost, J.; Wray, K.; Santos, A.; Porto, G.; Repapi, E.; Gray, N.; Draper, S.; Ashley, N.; Soilleux, E.; Olinga, P.; Muckenthaler, M.; Hughes, J.; Rivella, S.; Milne, T.; Armitage, A.; Drakesmith, H.articleopenAccess
Set-2007Iron overload and immunityPorto, G.; De Sousa, M.articleopenAccess
5-Mar-2016Local iron homeostasis in the breast ductal carcinoma microenvironmentMarques, O.; Porto, G.; Rêma, A.; Faria, F.; Cruz Paula, A.; Gomez-Lazaro, M.; Silva, P.; Martins-Silva, B.; Lopes, C.articleopenAccess
2015Lymphocyte gene expression signatures from patients and mouse models of hereditary hemochromatosis reveal a function of HFE as a negative regulator of CD8+ T-lymphocyte activation and differentiation in vivoCosta, M.; Cruz, E.; Oliveira, S.; Benes, Vl.; Ivacevic, T.; Silva, M.; Vieira, I.; Dias, F.; Fonseca, S.; Gonçalves, M.; Lima, M.; Leitão, C.; Muckenthaler, M.; Pinto, J.; Porto, G.articleopenAccess
6-Nov-2008A new 500 kb haplotype associated with high CD8+ T-lymphocyte numbers predicts a less severe expression of hereditary hemochromatosisCruz, E.; Whittington, C.; Krikler, S.; Mascarenhas, C.; Lacerda, R.; Vieira, J.; Porto, G.articleopenAccess
2013Non-Transferrin-Bound Iron (NTBI) Uptake by T Lymphocytes: Evidence for the Selective Acquisition of Oligomeric Ferric Citrate SpeciesArezes, J.; Costa, M.; Vieira, I.; Dias, V.; Kong, X.; Fernandes, R.; Vos, M.; Carlsson, A.; Rikers, Y.; Porto, G.; Rangel, M.; Hider, R.; Pinto, J.articleopenAccess
2014Physiological implications of NTBI uptake by T lymphocytesPinto, J.; Arezes, J.; Dias, V.; Oliveira, S.; Vieira, I.; Costa, M.; Vos, M.; Carlsson, A.; Rikers, Y.; Rangel, M.; Porto, G.articleopenAccess
Out-2005A Portuguese patient homozygous for the -25G>A mutation of the HAMP promoter shows evidence of steady-state transcription but fails to up-regulate hepcidin levels by iron.Porto, G.; Roetto, A.; Daraio, F.; Pinto, J.; Almeida, S.; Bacelar, C.; Nemeth, E.; Ganz, T.; Camaschella, C.articleopenAccess
Mar-2006A study of 82 extended HLA haplotypes in HFE-C282Y homozygous hemochromatosis subjects: relationship to the genetic control of CD8+ T-lymphocyte numbers and severity of iron overloadCruz, E.; Vieira, J.; Almeida, S.; Lacerda, R.; Gartner, A.; Cardoso, C.; Alves, H.; Porto, G.articleopenAccess
2005The soluble transferrin receptor as a marker of iron homeostasis in normal subjects and in HFE-related hemochromatosisBrandâo, M.; Oliveira, J.; Bravo, F.; Reis, J.; Garrido, I.; Porto, G.articleopenAccess