Utilize este identificador para referenciar este registo: http://hdl.handle.net/10400.16/1646
Título: Pulmonary Hypertension in Portugal: First Data from a Nationwide Registry
Autor: Baptista, R.
Meireles, J.
Agapito, A.
Castro, G.
Marinho-Silva, A:
Shiang, T.
Gonçalves, F.
Rubalo-Martins, S.
Nunes-Diogo, A.
Reis, A.
Data: 2013
Editora: Hindawi Publishing Corporation
Citação: Rui Baptista, José Meireles, Ana Agapito, et al., “Pulmonary Hypertension in Portugal: First Data from a Nationwide Registry,” BioMed Research International, vol. 2013, Article ID 489574, 8 pages, 2013. doi:10.1155/2013/489574
Resumo: Introduction. Pulmonary arterial hypertension (PAH) is a rare disease that must be managed in specialized centers; therefore, the availability of epidemiological national data is critical. Methods. We conducted a prospective, observational, and multicenter registry with a joint collaboration from five centers from Portugal and included adult incident patients with PAH or chronic thromboembolic pulmonary hypertension (CTEPH). Results. Of the 79 patients enrolled in this study, 46 (58.2%) were classified as PAH and 33 patients (41.8%) as CTEPH. PAH patients had a mean age of 43.4 ± 16.4 years. Idiopathic PAH was the most common etiology (37%). At presentation, PAH patients had elevated right atrial pressure (RAP) (7.7 ± 5.9 mmHg) and mean pulmonary vascular resistance (11.4 ± 6.5 Wood units), with a low cardiac index (2.7 ± 1.1 L·min−1·m−2); no patient was under selective pulmonary vasodilators; however, at follow-up, most patients were on single (50%), double (28%), or triple (9%) combination vasodilator therapy. One-year survival was 93.5%, similar to CTEPH patients (93.9%), that were older (60.0 ± 12.5 years) and had higher RAP (11.0 ± 5.2 mmHg, ). Conclusions. We describe for the first time nationwide data on the diagnosis, management, and prognosis of PAH and CTEPH patients in Portugal. Clinical presentation and outcomes are comparable with those reported on other national registries.
Peer review: yes
URI: http://hdl.handle.net/10400.16/1646
DOI: http://dx.doi.org/10.1155/2013/489574
ISSN: 2314-6141
Versão do Editor: http://www.hindawi.com/journals/bmri/2013/489574/cta/
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