Utilize este identificador para referenciar este registo: http://hdl.handle.net/10400.16/1667
Título: Sezary Syndrome presenting with leonine facies and treated with low-dose subcutaneous alemtuzumab
Autor: Oliveira, A.
Lobo, I.
Alves, R.
Lima, M.
Selores, M.
Data: 2012
Editora: University of California
Citação: Dermatology Online Journal 17 (11): 6
Resumo: Cutaneous T-cell lymphomas (CTCL) comprise a group of diseases characterized by the accumulation of malignant T cells within the skin. Sezary syndrome represents an aggressive form of CTCL, in which the skin is diffusely affected and the peripheral blood is involved. It is characterized by the triad of generalized erythroderma, lymphadenopathy, and neoplastic T cells (Sezary cells) in the skin, lymph nodes, and peripheral blood. Leonine facies is rare and corresponds to the morphologic manifestation of diffuse dermal infiltration of the face. It can occur in cutaneous T-cell lymphomas that progress during years without therapy. We present the case of a 54-year-old man with Sezary syndrome presenting with leonine facies, unresponsive to conventional therapies; he exhibited a promising response to subcutaneous low-dose alemtuzumab.
Peer review: yes
URI: http://hdl.handle.net/10400.16/1667
ISSN: 1087-2108
Versão do Editor: http://escholarship.org/uc/item/7f79243d
Aparece nas colecções:PT - Artigos publicados em revistas indexadas na Medline
SHC - Artigos publicados em revistas indexadas na Medline
SD - Artigos publicados em revistas indexadas na Medline

Ficheiros deste registo:
Ficheiro Descrição TamanhoFormato 
Sezary Syndrome presenting with leonine facies and treated with low-dose subcutaneous alemtuzumab.pdf250,76 kBAdobe PDFVer/Abrir


FacebookTwitterDeliciousLinkedInDiggGoogle BookmarksMySpace
Formato BibTex MendeleyEndnote Degois 

Todos os registos no repositório estão protegidos por leis de copyright, com todos os direitos reservados.