Utilize este identificador para referenciar este registo: http://hdl.handle.net/10400.16/1983
Título: 17-Week Delay Surgery after Chemoradiation in Rectal Cancer with Complete Pathological Response
Autor: Santos, M.
Gomes, M.
Moreno, F.
Rocha, A.
Lopes, C.
Data: 2015
Editora: Hindawi Publishing Corporation
Citação: Case Rep Surg. 2015;2015:816491
Resumo: Neoadjuvant chemoradiation (CRT) followed by curative surgery still remains the standard of care for locally advanced rectal cancer (LARC). The main purpose of this multimodal treatment is to achieve a complete pathological tumor response (ypCR), with better survival. The surgery delay after CRT completion seems to increase tumor response and ypCR rate. Usually, time intervals range from 8 to 12 weeks, but the maximum tumor regression may not be seen in rectal adenocarcinomas until several months after CRT. About this issue, we report a case of a 52-year-old man with LARC treated with neoadjuvant CRT who developed, one month after RT completion, an acute myocardial infarction. The need to increase the interval between CRT and surgery for 17 weeks allowed a curative surgery without morbidity and an unexpected complete tumor response in the resected specimen (given the parameters presented in pelvic magnetic resonance imaging (MRI) performed 11 weeks after radiotherapy completion).
Peer review: yes
URI: http://hdl.handle.net/10400.16/1983
DOI: 10.1155/2015/816491
ISSN: 2090-6919
Versão do Editor: http://www.hindawi.com/journals/cris/2015/816491/
Aparece nas colecções:SAP - Artigos publicados em revistas indexadas na Medline
SRD - Artigos publicados em revistas indexadas na Medline
SG - Artigos publicados em revistas indexadas na Medline
Cir.1 - Artigos publicados em revistas indexadas na Medline

Ficheiros deste registo:
Ficheiro Descrição TamanhoFormato 
17-Week Delay Surgery after Chemoradiation in Rectal Cancer.pdf3,41 MBAdobe PDFVer/Abrir


FacebookTwitterDeliciousLinkedInDiggGoogle BookmarksMySpace
Formato BibTex MendeleyEndnote Degois 

Todos os registos no repositório estão protegidos por leis de copyright, com todos os direitos reservados.