Utilize este identificador para referenciar este registo: http://hdl.handle.net/10400.16/2248
Título: Diagnosis of monoclonal gammopathy of renal significance
Autor: Correia, S.
Santos, S.
Martins, L.
Santos, J.
Palavras-chave: Monoclonal gammopathy of renal significance
M protein
Renal pathology
Treatment.
Data: 2018
Editora: Sociedade Portuguesa de Nefrologia
Citação: Port J Nephrol Hypert 2018; 32(1): 52-56
Resumo: Monoclonal gammopathies are a heterogeneous group of disorders characterized by clonal proliferation of immunoglobulin produced by B-lymphocytes or plasma cell clone. The term monoclonal gammopathy of renal significance (MGRS) was introduced to distinguish monoclonal gammopathies that result in the development of kidney disease from those that are benign. Screening for monoclonal immunoglobulin and an appropriate hematologic workup are fundamental and sometimes a difficult challenge, with therapeutic and prognostic implications. Kidney biopsy is essential to determine the exact nature of the lesion and to evaluate the severity of renal disease. In this review we discuss the clinical and pathologic features of MGRS, highlighting the most diagnostic difficulties and current therapeutic options.
Peer review: yes
URI: http://hdl.handle.net/10400.16/2248
ISSN: 2183-1289
Versão do Editor: http://www.spnefro.pt/rpnh/browse_all_issues/67_volume_32_number_1
Aparece nas colecções:SNEF - Artigos publicados em revistas não indexadas na Medline

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