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Browsing by Author "Salgueiro, Paulo"

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  • 3% polidocanol foam sclerotherapy versus hemorrhoidal artery ligation with recto anal repair in hemorrhoidal disease grades II-III: a randomized, pilot trial
    Publication . Neves, Sara; Falcao, Daniela; Povo, Ana; Castro-Poças, Fernando; Oliveira, Jorge; Salgueiro, Paulo
    Purpose: Polidocanol foam sclerotherapy (SP) versus doppler-guided hemorrhoidal artery ligation with recto-anal repair (HAL-RAR) in the treatment of hemorrhoidal disease (HD) was analyzed. Methods: A prospective, randomized study including patients with HD grades II and III was performed. Participants were randomly assigned (1:1) into SP or HAL-RAR, during a recruitment period between September 2019 and February 2020. Therapeutic success (Sodergren's and bleeding scores) was the primary outcome. Other outcomes evaluated included complications and implication in the professional life. Efficacy and safety outcomes were evaluated during the 8 weeks after surgery or the final SP session. Results: Forty-six patients were allocated either to SP (n=22) or HAL-RAR (n=24). Most patients achieved therapeutic success (SP 100% vs. HAL-RAR 90.9%, p=0.131). Complete success was higher in the SP group (91.7% vs. 68.2%, p=0.045) and SP patients had less complications (25% vs. 68.2%, p=0.003). HAL-RAR had a greater negative impact on work activity of the patient. Conclusion: SP was more effective and safer than HAL-RAR. SP patients had less impact on their work activity. Clinical trials identifier NCT04675177.
    2023-03Journal article Open access Show more
  • N-glicosilação do recetor das células t: um novo mecanismo molecular na patogénese da doença inflamatória intestinal
    Publication . Dias, Ana; Catarino, Telmo; Lago, Paula; Marcos-Pinto, Ricardo; Salgueiro, Paulo; Almeida, Catarina; Fonseca, Sónia; Lima, Margarida; Vilanova, Manuel; Dinis-Ribeiro, Mário; Reis, Celso; Pinho, Salomé
    2014-06-27Conference object Open access Show more
  • Portuguese Society of Gastroenterology Consensus on the Diagnosis and Management of Hemorrhoidal Disease
    Publication . Salgueiro, Paulo; Caetano, Ana Célia; Oliveira, Ana Maria; Rosa, Bruno; Mascarenhas-Saraiva, Miguel; Ministro, Paula; Amaro, Pedro; Godinho, Rogério; Coelho, Rosa; Gaio, Rúben; Fernandes, Samuel; Fernandes, Vítor; Castro-Poças, Fernando
    Hemorrhoidal disease (HD) is a frequent health problem with considerable repercussions on patients' quality of life. However, much of the clinical practice related to HD is based on knowledge without scientific evidence and supported largely by empirical experience of the physician who deals with this pathology. As in other countries, the goal of this consensus is to establish statements supported by solid scientific evidence and whose purpose will be to standardize and guide the diagnosis and management of HD both in the general population and in some particular groups of patients.
    2020Journal article Open access Show more