Browsing by Issue Date, starting with "2005-12"
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- Radial basis function neural networks versus fuzzy models to predict return of consciousness after general anesthesiaPublication . NUNES, C.S.; MENDONCA, T.F.; AMORIM, P.; FERREIRA, D.A.; ANTUNES, L.M.Conf Proc IEEE Eng Med Biol Soc. 2004;2:865-8. Radial basis function neural networks versus fuzzy models to predict return of consciousness after general anesthesia. Nunes CS, Mendonca TF, Amorim P, Ferreira DA, Antunes LM. Dept. of Appl. Math., Porto Univ., Portugal. Abstract This work presents two modelling techniques to predict return of consciousness (ROC) after general anaesthesia, considering the effect concentration of the anaesthetic drug at awakening. First, several clinical variables were statistically analysed to determine their correlation with the awakening concentration. The anaesthetic and the analgesic mean dose during surgery, and the age of the patient, proved to have significantly high correlation coefficients. Variables like the mean bispectral index value during surgery, duration of surgery did not present a statistical relation with ROC. Radial basis function (RBF) neural networks were trained relating different sets of clinical values with the anaesthetic drug effect concentration at awakening. Secondly, fuzzy models were built using an adaptive network-based fuzzy inference system (ANFIS) also relating different sets of variables. Clinical data was used to train and test the models. The fuzzy models and RBF neural networks proved to have good prediction properties and balanced results. PMID: 17271814 [PubMed]
- Results from the ARTEMIS DISK Global Antifungal Surveillance Study: a 6.5‐year analysis of susceptibilities of Candida and other yeast species to fluconazole and voriconazole by standardized disk diffusion testing.Publication . PFALLER, M.A.; DIEKEMA, D.J.; RINALDI, M.G.; BARNES, R.; HU, B.; VESELOV, A.V.; TIRABOSCHI, N.; NAGY, E.; GIBBS, D.L.J Clin Microbiol. 2005 Dec;43(12):5848-59. Results from the ARTEMIS DISK Global Antifungal Surveillance Study: a 6.5-year analysis of susceptibilities of Candida and other yeast species to fluconazole and voriconazole by standardized disk diffusion testing. Pfaller MA, Diekema DJ, Rinaldi MG, Barnes R, Hu B, Veselov AV, Tiraboschi N, Nagy E, Gibbs DL. Medical Microbiology Division, C606 GH, Department of Pathology, University of Iowa College of Medicine, Iowa City, IA 52242, USA. michael-pfaller@uiowa.edu Abstract Fluconazole in vitro susceptibility test results for 140,767 yeasts were collected from 127 participating investigators in 39 countries from June 1997 through December 2003. Data were collected on 79,343 yeast isolates tested with voriconazole from 2001 through 2003. All investigators tested clinical yeast isolates by the CLSI (formerly NCCLS) M44-A disk diffusion method. Test plates were automatically read and results were recorded with the BIOMIC Vision Image Analysis System. Species, drug, zone diameter, susceptibility category, and quality control results were collected quarterly via e-mail for analysis. Duplicate (the same patient, same species, and same susceptible-resistant biotype profile during any 7-day period) and uncontrolled test results were not analyzed. The 10 most common species of yeasts all showed less resistance to voriconazole than to fluconazole. Candida krusei showed the largest difference, with over 70% resistance to fluconazole and less than 8% to voriconazole. All species of yeasts tested were more susceptible to voriconazole than to fluconazole, assuming proposed interpretive breakpoints of > or =17 mm (susceptible) and < or =13 mm (resistant) for voriconazole. MICs reported in this study were determined from the zone diameter in millimeters from the continuous agar gradient around each disk, which was calibrated with MICs determined from the standard CLSI M27-A2 broth dilution method by balanced-weight regression analysis. The results from this investigation demonstrate the broad spectrum of the azoles for most of the opportunistic yeast pathogens but also highlight several areas where resistance may be progressing and/or where previously rare species may be "emerging." PMID: 16333066 [PubMed - indexed for MEDLINE]PMCID: PMC1317207Free
- Evaluative and discriminative properties of the Portuguese MacNew Heart Disease Health‐related Quality of Life Questionnaire.Publication . LEAL, A.; PAIVA, C.; HOFER, S.; AMADO, J.; GOMES, L.; OLDRIDGE, N.Qual Life Res. 2005 Dec;14(10):2335-41. Evaluative and discriminative properties of the Portuguese MacNew Heart Disease Health-related Quality of Life Questionnaire. Leal A, Paiva C, Höfer S, Amado J, Gomes L, Oldridge N. Cardiac Rehabilitation Unit, Hospital Sto António Porto, Largo Prof Abel Salazar 400, Portugal. antl@clix.pt Abstract The aim of this study was to validate the Portuguese version of the self-administered MacNew Heart Disease Health-related Quality of Life (MacNew) questionnaire in patients after diagnosis of acute coronary syndrome. The MacNew, with a Global score and physical, emotional and social subscales, the Short Form SF-36 (SF-36) and the Hospital Anxiety and Depression Scale (HADS) were completed at baseline by 150 patients and again by 48 clinically stable patients 2-3 weeks later. A cohort of 50 different patients completed the same questionnaires before and after a cardiac rehabilitation program in order to examine responsiveness. Acceptance of the MacNew by the patients was good and the three factor model was substantiated and explained 52.2% of the variance. Internal consistency, intra-class-correlation, and test-retest reliability each exceeded 0.72. The predicted construct validity hypotheses were partially confirmed. The discriminative validity of the MacNew was confirmed with significantly higher MacNew scores for patients with normal left ventricular function, with improved health status, and who were not anxious or depressed. Even though MacNew scores improved significantly following cardiac rehabilitation, the evaluative validity of the MacNew was less robust with small responsiveness statistics. The Portuguese version of the MacNew HRQL questionnaire appears to be a reliable, valid, and moderately responsive instrument to evaluate health-related quality of life after diagnosis of acute coronary syndrome. PMID: 16328913 [PubMed - indexed for MEDLINE]
- European best practice guidelines for peritoneal dialysis. 1 General guidelines.Publication . Dombros, N.; Dratwa, M.; Feriani, M.; Gokal, R.; Heimbürger, O.; Krediet, R.; Plum, J.; Rodrigues, A.; Selgas, R.; Struijk, D.; Verger, C.
- European best practice guidelines for peritoneal dialysis. 7 Adequacy of peritoneal dialysis.Publication . Dombros, N.; Dratwa, M.; Feriani, M.; Gokal, R.; Heimbürger, O.; Krediet, R.; Plum, J.; Rodrigues, A.; Selgas, R.; Struijk, D.; Verger, C.
- European best practice guidelines for peritoneal dialysis. 9 PD and transplantation.Publication . Dombros, N.; Dratwa, M.; Feriani, M.; Gokal, R.; Heimbürger, O.; Krediet, R.; Plum, J.; Rodrigues, A.; Selgas, R.; Struijk, D.; Verger, C.
- European best practice guidelines for peritoneal dialysis. 2 The initiation of dialysis.Publication . Dombros, N.; Dratwa, M.; Gokal, R.; Heimbürger, O.; Krediet, R.; Plum, J.; Rodrigues, A.; Selgas, R.; Struijk, D.; Verger, C.
- Regular clinical use bispectral índex monitoring may result in lighter depth of anesthesia as reflected in average higher bispectral index valuesPublication . NUNES, C.S.; FERREIRA, D.A.; ANTUNES, L.M.; AMORIM, P.Anesthesiology. 2005 Dec;103(6):1320-1. Regular clinical use bispectral index monitoring may result in lighter depth of anesthesia as reflected in average higher bispectral index values. Nunes CS, Ferreira DA, Antunes LM, Amorim P. PMID: 16306760 [PubMed - indexed for MEDLINE]
- European best practice guidelines for peritoneal dialysis. 8 Nutrition in peritoneal dialysisPublication . Dombros, N.; Dratwa, M.; Feriani, M.; Gokal, R.; Heimbürger, O.; Krediet, R.; Plum, J.; Rodrigues, A.; Selgas, R.; Struijk, D.; Verger, C.
- European best practice guidelines for peritoneal dialysis. 5 Peritoneal dialysis solutionsPublication . Dombros, N.; Dratwa, D.; Feriani, M.; Gokal, R.; Heimbürger, O.; Krediet, R.; Plum, J.; Rodrigues, A.; Selgas, R.; Struijk, D.; Verger, C.