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Da Silva Machado, Humberto José

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  • Adrenal Crisis During Cesarean Section in a Patient With Primary Adrenal Insufficiency
    Publication . Pestana, Inês; Guimarães, Henrique; Saraiva, Alexandra; Veiga, Dalila; Machado, Humberto
    Congenital adrenal hyperplasia (CAH) is a type of primary adrenal insufficiency (AI) that predisposes to adrenal crisis (AC) during stress. We describe a case of a primipara with CAH who was admitted in labor. To prevent AC, glucocorticoid replacement was given according to guidelines. Due to fetal decelerations, an emergency C-section was performed under general anesthesia following which refractory hypotension emerged. The diagnosis of AC was considered, and hydrocortisone was given with sustained hemodynamic improvement. AC is a life-threatening emergency whose diagnosis requires a high index of suspicion. Despite adequate steroid coverage, additional stressors may precipitate AC, so it is of paramount importance that anesthesiologists consider this emergency