Loading...
2 results
Search Results
Now showing 1 - 2 of 2
- Cardiovascular Complications of COVID-19 InfectionPublication . Trêpa, Maria; Hipólito-Reis, António; Oliveira, MarioIntroduction: Reports of cardiovascular complications related to the COVID-19 infection have been frequent. Methods: Narrative review for relevant articles on the topic. The classic cardiovascular risk factors, like age, obesity, diabetes, and hypertension are associated with adverse outcomes in COVID-19 patients. Cardiovascular complications can have a diverse clinical presentation including silent myocardial injury, acute coronary syndromes, thromboembolism, cardiac arrhythmias, and heart failure. There are multiple mechanisms of cardiac injury that are not mutually exclusive. The approach to diagnosis and management should be carried out according to usual practice, while considering the particularities of COVID-19 infection. Conclusion: The interaction between SARS-CoV-2 and the heart is complex and is manifested in multiple ways. Regardless of the clinical presentation, cardiac complications convey a worse prognosis. Patients should be actively monitored and treated accordingly.
- Impact of the COVID-19 pandemic on hospitalizations for acute coronary syndromes: a multinational studyPublication . Araiza-Garaygordobil, D; Montalto, C; Martinez-Amezcua, P; Cabello-Lopez, A; Gopar-Nieto, R; Alabrese, R; Almaghraby, A; Catoya-Villa, S; Chacon-Diaz, M; Kaufmann, C C; Corbi-Pascual, M; Deharo, P; El-Tahlawi, M; Elgohari-Abdelwahab, A; Guerra, F; Jarakovic, M; Martinez-Gomez, E; Moderato, L; Montero, S; Morejon-Barragan, P; Omar, A M; Jorge-Pérez, P; Przybyło, P; Selim, E; Sinan, U Y; Stratinaki, M; Tica, O; Trêpa, Maria; Uribarri, A; Uzokov, J; Wilk, K; Czerwińska-Jelonkiewicz, K; Sionis, A; Gierlotka, M; Leonardi, S; Krychtiuk, K A; Tavazzi, GBackground: COVID-19 has challenged the health system organization requiring a fast reorganization of diagnostic/therapeutic pathways for patients affected by time-dependent diseases such as acute coronary syndromes (ACS). Aim: To describe ACS hospitalizations, management, and complication rate before and after the COVID-19 pandemic was declared. Design: Ecological retrospective study. Methods: We analyzed aggregated epidemiological data of all patients > 18 years old admitted for ACS in twenty-nine hub cardiac centers from 17 Countries across 4 continents, from December 1st, 2019 to April 15th, 2020. Data from December 2018 to April 2019 were used as historical period. Results: A significant overall trend for reduction in the weekly number of ACS hospitalizations was observed (20.2%; 95% confidence interval CI [1.6, 35.4] P = 0.04). The incidence rate reached a 54% reduction during the second week of April (incidence rate ratio: 0.46, 95% CI [0.36, 0.58]) and was also significant when compared to the same months in 2019 (March and April, respectively IRR: 0.56, 95%CI [0.48, 0.67]; IRR: 0.43, 95%CI [0.32, 0.58] p < 0.001). A significant increase in door-to-balloon, door-to-needle, and total ischemic time (p <0.04 for all) in STEMI patents were reported during pandemic period. Finally, the proportion of patients with mechanical complications was higher (1.98% vs. 0.98%; P = 0.006) whereas GRACE risk score was not different. Conclusions: Our results confirm that COVID-19 pandemic was associated with a significant decrease in ACS hospitalizations rate, an increase in total ischemic time and a higher rate of mechanical complications on a international scale.