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Preconceptional immunity and congenital cytomegalovirus infection – A serologic pitfall

dc.contributor.authorFerreira, Joana
dc.contributor.authorFonseca, José Luís
dc.contributor.authorVieira, Maria João
dc.date.accessioned2021-10-04T10:02:43Z
dc.date.available2021-10-04T10:02:43Z
dc.date.issued2021-03
dc.description.abstractCongenital cytomegalovirus infections are the most prevalent intrauterine infections worldwide and result from maternal primary or non-primary infections. Diagnosis of primary cytomegalovirus infection during pregnancy is considered reliable and mainly relies on maternal serology. However, diagnosis of non-primary cytomegalovirus infection is more questionable. Herein is reported the case of a 34-week-old male newborn with congenital cytomegalovirus infection of a mother with preconceptional immunity. The organism was identified in urine by polymerase chain reaction in the first week of life. Maternal peripartum serology was the same as prior to conception. This case highlights the pitfalls of cytomegalovirus serology interpretation in non-primary infection during pregnancy. Clinicians should be aware of this and consider congenital cytomegalovirus infection, particularly when suggestive signs are present.pt_PT
dc.description.versioninfo:eu-repo/semantics/publishedVersionpt_PT
dc.identifier.citationFerreira J, Fonseca JL, Vieira MJ, Nascer e Crescer - Birth and Growth Medical Journal 2021;30(1): 56-60. doi:10.25753/BirthGrowthMJ.v30.i1.18699pt_PT
dc.identifier.doi10.25753/BirthGrowthMJ.v30.i1.18699pt_PT
dc.identifier.issn2183-9417
dc.identifier.urihttp://hdl.handle.net/10400.16/2506
dc.language.isoengpt_PT
dc.peerreviewedyespt_PT
dc.publisherCentro Hospitalar Universitário do Portopt_PT
dc.relation.publisherversionhttps://revistas.rcaap.pt/nascercrescer/article/view/18699pt_PT
dc.rights.urihttp://creativecommons.org/licenses/by-nc/4.0/pt_PT
dc.subjectcytomegaloviruspt_PT
dc.subjectcongenital cytomegalovirus infectionpt_PT
dc.subjectserologypt_PT
dc.titlePreconceptional immunity and congenital cytomegalovirus infection – A serologic pitfallpt_PT
dc.title.alternativeImunidade pré-concecional e infeção congénita por citomegalovírus – Uma armadilha serológicapt_PT
dc.typejournal article
dspace.entity.typePublication
oaire.citation.conferencePlacePorto, Portugalpt_PT
oaire.citation.endPage60pt_PT
oaire.citation.issue1pt_PT
oaire.citation.startPage56pt_PT
oaire.citation.titleNascer e Crescer - Birth and Growth Medical Journalpt_PT
oaire.citation.volume30pt_PT
rcaap.rightsopenAccesspt_PT
rcaap.typearticlept_PT

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