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Anterior Chamber Flare as an Objective and Quantitative Noninvasive Method for Oculopathy in Transthyretin V30M Amyloidosis Patients

2018-09-20Journal article Open access
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dc.contributor.authorBeirão, J.
dc.contributor.authorMiranda, V.
dc.contributor.authorPinheiro-Torres, B.
dc.contributor.authorCoelho, J.
dc.contributor.authorMenéres, M.
dc.contributor.authorMenéres, P.
dc.date.accessioned2019-11-19T14:44:22Z
dc.date.available2019-11-19T14:44:22Z
dc.date.issued2018-09-20
dc.description.abstractPurpose. Assess the aqueous humor flare in transthyretin V30M amyloidosis patients (ATTRV30M). Materials and Methods. This is a retrospective, cross-sectional, noninterventional comparative study including 28 ATTRV30M patients with a unilateral scalloped iris. For comparative analysis, the fellow eye, the nonscalloped iris eye, from each patient was used as control. All patients underwent aqueous humor flare meter and intraocular pressure (IOP) measurements. Results. Mean aqueous humor flare was significantly higher in the eyes with the scalloped iris than the control group with the nonscalloped iris (14.1 ± 2.2 versus 6.5 ± 0.9 pc/ms, respectively). No significant differences in IOP were found in the scalloped iris eyes than those in the nonscalloped iris control group (17.1 ± 0.8 versus 16.8 ± 0.7 mmHg, respectively). No significant correlation was not found between the flare and the IOP value within groups. Conclusions. In this study, aqueous humor flare values in the scalloped iris eyes may be a valid marker for controlling the stage of the oculopathy in ATTRV30M patients.pt_PT
dc.description.versioninfo:eu-repo/semantics/publishedVersionpt_PT
dc.identifier.citationJ Ophthalmol. 2018 Sep 20;2018:3727543pt_PT
dc.identifier.doi10.1155/2018/3727543pt_PT
dc.identifier.issn2090-004X
dc.identifier.issn2090-0058
dc.identifier.urihttp://hdl.handle.net/10400.16/2301
dc.language.isoengpt_PT
dc.peerreviewedyespt_PT
dc.publisherHindawi Publishing Corporationpt_PT
dc.relation.publisherversionhttps://www.hindawi.com/journals/joph/2018/3727543/pt_PT
dc.rights.urihttp://creativecommons.org/licenses/by-nc/4.0/pt_PT
dc.titleAnterior Chamber Flare as an Objective and Quantitative Noninvasive Method for Oculopathy in Transthyretin V30M Amyloidosis Patientspt_PT
dc.typejournal article
dspace.entity.typePublication
oaire.citation.conferencePlaceUnited States of Americapt_PT
oaire.citation.endPage5pt_PT
oaire.citation.startPage3727543pt_PT
oaire.citation.titleJournal of ophthalmologypt_PT
oaire.citation.volume2018pt_PT
person.familyNameBeirão
person.givenNameJoão Nuno Melo
person.identifier.ciencia-id0214-5233-EE9D
person.identifier.orcid0000-0001-8642-7010
rcaap.rightsopenAccesspt_PT
rcaap.typearticlept_PT
relation.isAuthorOfPublication03b98348-ce82-4043-bb58-db089fcc21d6
relation.isAuthorOfPublication.latestForDiscovery03b98348-ce82-4043-bb58-db089fcc21d6

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