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Oral ulcer as presentation of cavitating pulmonary tuberculosis

2020-10-01Journal article Open access
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dc.contributor.authorFragoso, Joana
dc.contributor.authorOliveira, Mariana Marques
dc.contributor.authorGonçalves, Celina
dc.contributor.authorMéndez, Josefina
dc.contributor.authorSarmento-Castro, Rui
dc.date.accessioned2021-12-09T14:13:32Z
dc.date.available2021-12-09T14:13:32Z
dc.date.issued2020-10-01
dc.description.abstractTuberculosis is an indolent infection that can invade any organ. Although the most frequent form of presentation is pulmonary, it can have an extra-pulmonary presentation, including rare cases of oral tuberculosis. We present a clinical case of a 44 year-old man, active smoker, with an ulcerated lesion on the posterior third of the tongue, initially interpreted as a probable neoplasm. The pathological study of the biopsy performed on the lesion, showed alterations compatible with a chronic granulomatous process and the presence of acid-fast bacilli. The concomitant diagnosis of pulmonary tuberculosis was made in a subsequent study. The patient started therapy with isoniazid, rifampin, pyrazinamide and ethambutol with complete resolution of the oral lesion and pulmonary tuberculosis. This case exemplifies the importance of including tuberculosis in the differential diagnosis of ulcerated and neoformative lesions and the value of performing a microbiological study alongside the pathological one.pt_PT
dc.description.versioninfo:eu-repo/semantics/publishedVersionpt_PT
dc.identifier.citationFragoso J, Oliveira MM, Gonçalves C, Méndez J, Sarmento-Castro R. Oral ulcer as presentation of cavitating pulmonary tuberculosis. IDCases. 2020;22:e00976. doi:10.1016/j.idcr.2020.e00976pt_PT
dc.identifier.doi10.1016/j.idcr.2020.e00976pt_PT
dc.identifier.issn2214-2509
dc.identifier.urihttp://hdl.handle.net/10400.16/2645
dc.language.isoengpt_PT
dc.peerreviewedyespt_PT
dc.publisherElsevierpt_PT
dc.relation.publisherversionhttps://www.sciencedirect.com/science/article/pii/S2214250920302845?via%3Dihubpt_PT
dc.rights.urihttp://creativecommons.org/licenses/by-nc-nd/4.0/pt_PT
dc.subjectMycobacterium tuberculosispt_PT
dc.subjectPulmonary tuberculosispt_PT
dc.subjectTuberculous oral ulcerpt_PT
dc.titleOral ulcer as presentation of cavitating pulmonary tuberculosispt_PT
dc.typejournal article
dspace.entity.typePublication
oaire.citation.conferencePlaceNetherlandspt_PT
oaire.citation.startPagee00976pt_PT
oaire.citation.titleIDCasespt_PT
oaire.citation.volume22pt_PT
person.familyNameFragoso
person.familyNameGonçalves
person.givenNameJoana
person.givenNameCelina
person.identifier.ciencia-idCF17-9C79-D524
person.identifier.orcid0000-0001-5566-9981
person.identifier.orcid0000-0002-0194-5140
rcaap.rightsopenAccesspt_PT
rcaap.typearticlept_PT
relation.isAuthorOfPublication524b3307-b34f-4a35-b836-1ee315ba6eff
relation.isAuthorOfPublicationb227b162-3a60-4d8f-b783-f1d3d5f3f3e1
relation.isAuthorOfPublication.latestForDiscovery524b3307-b34f-4a35-b836-1ee315ba6eff

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