Publication
Endoscopic Ultrasound-Guided Ablation of Focal Pancreatic Lesions: The GRUPUGE Perspective
| dc.contributor.author | Bispo, Miguel | |
| dc.contributor.author | Caldeira, Ana | |
| dc.contributor.author | Leite, Sílvia | |
| dc.contributor.author | Marques, Susana | |
| dc.contributor.author | Moreira, Teresa | |
| dc.contributor.author | Moutinho-Ribeiro, Pedro | |
| dc.contributor.author | Nunes, Nuno | |
| dc.date.accessioned | 2021-12-06T15:25:54Z | |
| dc.date.available | 2021-12-06T15:25:54Z | |
| dc.date.issued | 2020 | |
| dc.description.abstract | Focal pancreatic lesions include a heterogeneous group of solid and cystic lesions, with different natures and variable clinical, imagiological, and pathological characteristics. Several endoscopic ultrasound (EUS)-guided ablative techniques have been tested during the last decade for the treatment of these pancreatic lesions, mostly consisting of the injection of ablative agents and, more recently, radiofrequency ablation. The most encouraging EUS-guided ablation outcomes are being reached in the treatment of some pancreatic cystic neoplasms and small (≤2 cm) pancreatic neuroendocrine tumours (pNETs). Data supporting a potential role of ablative therapies in the treatment of pancreatic ductal adenocarcinoma is still lacking. In this article, GRUPUGE presents an updated perspective of the potential role of EUS-guided ablation for the treatment of pancreatic cystic neoplasms and pNETs, addressing the selection criteria and technical issues of different techniques and analysing recent data on their safety and efficacy. | pt_PT |
| dc.description.abstract | As lesões focais do pâncreas integram grupos heterogéneos de lesões sólidas e quísticas, de diferentes naturezas e com características clínicas, imagiológicas e patológicas variáveis. Na última década foram avaliadas diversas técnicas ablativas guiadas por ecoendoscopia para o tratamento destas lesões pancreáticas focais, consistindo maioritariamente na injeção de agentes ablativos e, mais recentemente, na ablação por radiofrequência. Os resultados mais promissores das técnicas ablativas guiadas por ecoendoscopia têm surgido no tratamento de algumas lesões quísticas do pâncreas e pequenos tumores neuro-endócrinos pancreáticos (≤2 cm). Ainda existem poucos dados a suportar um potencial papel das terapêuticas ablativas no tratamento do adenocarcinoma ductal do pancreas. No presente artigo o GRUPUGE apresentada uma perspectiva atual do potencial papel da ablação guiada por ecoendoscopia no tratamento de neoplasias quísticas do pâncreas e de tumores neuro-endócrinos pancreáticos, focando aspectos relativos à seleção dos doentes, questões técnicas dos vários procedimentos disponíveis e analisando dados recentes relativos à sua segurança e eficácia. | pt_PT |
| dc.description.version | info:eu-repo/semantics/publishedVersion | pt_PT |
| dc.identifier.citation | Bispo M, Caldeira A, Leite S, et al. Endoscopic Ultrasound-Guided Ablation of Focal Pancreatic Lesions: The GRUPUGE Perspective. GE Port J Gastroenterol. 2020;27(6):410-416. doi:10.1159/000507895 | pt_PT |
| dc.identifier.doi | 10.1159/000507895 | pt_PT |
| dc.identifier.issn | 2387-1954 | |
| dc.identifier.issn | 2341-4545 | |
| dc.identifier.uri | http://hdl.handle.net/10400.16/2634 | |
| dc.language.iso | eng | pt_PT |
| dc.peerreviewed | yes | pt_PT |
| dc.publisher | Karger AG | pt_PT |
| dc.relation.publisherversion | https://www.karger.com/Article/FullText/507895 | pt_PT |
| dc.rights.uri | http://creativecommons.org/licenses/by-nc-nd/4.0/ | pt_PT |
| dc.subject | Chemoablation | pt_PT |
| dc.subject | Endoscopic ultrasound-guided ablation | pt_PT |
| dc.subject | Pancreatic cyst | pt_PT |
| dc.subject | Pancreatic mucinous neoplasm | pt_PT |
| dc.subject | Pancreatic neuroendocrine tumour | pt_PT |
| dc.subject | Radiofrequency ablation | pt_PT |
| dc.title | Endoscopic Ultrasound-Guided Ablation of Focal Pancreatic Lesions: The GRUPUGE Perspective | pt_PT |
| dc.title.alternative | Ablação Guiada por Ecoendoscopia de Lesões Focais do Pâncreas: Perspetiva do GRUPUGE | pt_PT |
| dc.type | journal article | |
| dspace.entity.type | Publication | |
| oaire.citation.conferencePlace | Portugal | pt_PT |
| oaire.citation.endPage | 416 | pt_PT |
| oaire.citation.issue | 6 | pt_PT |
| oaire.citation.startPage | 410 | pt_PT |
| oaire.citation.title | GE - Portuguese Journal of Gastroenterology | pt_PT |
| oaire.citation.volume | 27 | pt_PT |
| rcaap.rights | openAccess | pt_PT |
| rcaap.type | article | pt_PT |
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