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Kawasaki disease in a five-month-old infant

2021-06Journal article Open access
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dc.contributor.authorMaciel, Juliana
dc.contributor.authorMeireles, Daniel
dc.contributor.authorMagalhães, Mariana
dc.contributor.authorGonçalves, Sara
dc.contributor.authorRibeiro Fernandes, Sofia
dc.contributor.authorFernandes, Paula Cristina
dc.date.accessioned2021-11-04T09:42:23Z
dc.date.available2021-11-04T09:42:23Z
dc.date.issued2021-06
dc.description.abstractIntroduction: Kawasaki disease, an acute self-limited vasculitis of small and medium arteries of unknown etiology, is the leading cause of heart disease in children in most developed countries. If untreated, it can lead to coronary artery dilatation and aneurysm, placing patients at risk for coronary thrombosis, myocardial infarction, or sudden death. Case Report: A previously healthy five-month-old boy presented with a history of respiratory symptoms and fever, being admitted for respiratory syncytial virus bronchiolitis. He maintained fever for five days associated with progressive clinical worsening and sequential development of conjunctival injection, cracked lips, swelling of hands and feet, and polymorphous rash of the limbs. Diagnostic procedures showed increased levels of inflammatory markers, hyponatremia, hypoalbuminemia, sterile pyuria, and aseptic meningitis. Despite an initial normal echocardiogram, Kawasaki disease was suspected and the boy started intravenous immunoglobulin on the fifth day. On the seventh day, echocardiogram showed signs of pancarditis and mild coronary artery ectasia and acetylsalicylic acid was started. The boy was discharged, but eight days later echocardiogram revealed major and diffuse coronary artery ectasia in a follow-up consultation and he was readmitted to start corticosteroid therapy. After five months, the boy displayed normalization of cardiac changes, without further complications. Comments: Kawasaki disease below six months of age is rare and associated with a high risk of coronary artery aneurysm. It is important to recognize the clinical and laboratory criteria associated with this entity and start early treatment, avoiding cardiac complications.pt_PT
dc.description.versioninfo:eu-repo/semantics/publishedVersionpt_PT
dc.identifier.citationMaciel J, Meireles D, Magalhães M, Gonçalves S, Ribeiro-Fernandes S, Fernandes PC, Nascer e Crescer - Birth and Growth Medical Journal 2021;30(2): 109-113. doi:10.25753/BirthGrowthMJ.v30.i2.19077pt_PT
dc.identifier.doi10.25753/BirthGrowthMJ.v30.i2.19077pt_PT
dc.identifier.issn2183-9417
dc.identifier.urihttp://hdl.handle.net/10400.16/2526
dc.language.isoengpt_PT
dc.peerreviewedyespt_PT
dc.publisherCentro Hospitalar Universitário do Portopt_PT
dc.relation.publisherversionhttps://revistas.rcaap.pt/nascercrescer/article/view/19077pt_PT
dc.rights.urihttp://creativecommons.org/licenses/by-nc/4.0/pt_PT
dc.subjectCoronary artery ectasiapt_PT
dc.subjectsudden infant death syndromept_PT
dc.subjectKawasaki Diseasept_PT
dc.subjectInfantpt_PT
dc.titleKawasaki disease in a five-month-old infantpt_PT
dc.title.alternativeDoença de Kwasaki num lactente de cinco mesespt_PT
dc.typejournal article
dspace.entity.typePublication
oaire.citation.conferencePlacePorto, Portugalpt_PT
oaire.citation.endPage113pt_PT
oaire.citation.issue2pt_PT
oaire.citation.startPage109pt_PT
oaire.citation.titleNascer e Crescer - Birth and Growth Medical Journalpt_PT
oaire.citation.volume30pt_PT
person.familyNameMaciel
person.familyNameMeireles
person.givenNameJuliana
person.givenNameDaniel
person.identifier.orcid0000-0002-4909-9502
person.identifier.orcid0000-0002-2377-7731
rcaap.rightsopenAccesspt_PT
rcaap.typearticlept_PT
relation.isAuthorOfPublicationc7f78a87-3fc0-42b6-8fb8-814b158f3572
relation.isAuthorOfPublication31a2c804-b065-4bc3-984b-b85875f86b0d
relation.isAuthorOfPublication.latestForDiscoveryc7f78a87-3fc0-42b6-8fb8-814b158f3572

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