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Malignant carotid body tumor: a case report

dc.contributor.authorDias da Silva, A.
dc.contributor.authorO`Donnel, S.
dc.contributor.authorGillespie, D.
dc.contributor.authorGoff, J.
dc.contributor.authorShriver, C.
dc.contributor.authorRich, N.
dc.date.accessioned2011-08-22T17:32:05Z
dc.date.available2011-08-22T17:32:05Z
dc.date.issued2000-10
dc.description.abstractAbstract Carotid body tumors (CBTs) have an unpredictable history with no correlation between histology and clinical behavior. Of reported cases since 1891, local and distant metastases appear in approximately 10% of cases and remain the hallmark of malignancy. Currently, there are not enough data to support a single treatment regimen for malignant CBTs. The reported case demonstrates some unanswered issues with regard to malignant CBTs to include lymph node dissection, the need for carotid resection, and the role of radiation therapy. A 46-year-old pathologist underwent a resection of a Shamblin I CBT, to include jugular lymph node sampling, without complication. There was lymph node involvement, and tumor cells were found on the margins of the pathologic specimen. Subsequent carotid resection with reversed interposition saphenous vein graft and modified neck dissection were performed again without complication. Follow-up at 4 years has been uneventful. Diagnosis of CBTs with the use of magnetic resonance angiography, magnetic resonance imaging, color flow duplex scanning, and the role of arteriography are reviewed. The current treatment options are discussed with reference to primary lymph node sampling, carotid resection, and neck dissection in malignant cases. This case demonstrates that the unpredictable nature of CBTs and their malignant potential warrant aggressive initial local treatment to include jugular lymph node sampling and complete tumor resection.por
dc.identifier.citationJ Vasc Surg. 2000 Oct;32(4):821-3por
dc.identifier.issn0741-5214
dc.identifier.urihttp://hdl.handle.net/10400.16/806
dc.language.isoengpor
dc.peerreviewedyespor
dc.publisherMosbypor
dc.relation.publisherversionhttp://www.sciencedirect.com/science/article/pii/S0741521400112340por
dc.titleMalignant carotid body tumor: a case reportpor
dc.typejournal article
dspace.entity.typePublication
oaire.citation.conferencePlaceUnited States of Americapor
oaire.citation.endPage823por
oaire.citation.issue32(4)por
oaire.citation.startPage821por
oaire.citation.titleJournal of Vascular Surgerypor
rcaap.rightsopenAccesspor
rcaap.typearticlepor

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