Repository logo
 
Publication

Ventilator-associated pneumonia diagnosis: a prioritization exercise based on multi-criteria decision analysis

2019Journal article Open access
Simple item page
dc.contributor.authorFerreira-Coimbra, João
dc.contributor.authorArdanuy, Carmen
dc.contributor.authorDiaz, Emili
dc.contributor.authorLeone, Marc
dc.contributor.authorDe Pascale, Gennaro
dc.contributor.authorPóvoa, Pedro
dc.contributor.authorPrat-Aymerich, Cristina
dc.contributor.authorSerrano-Garcia, Ricardo
dc.contributor.authorSolé-Violan, Jordi
dc.contributor.authorZaragoza, Rafael
dc.contributor.authorRello, Jordi
dc.date.accessioned2021-11-23T10:02:09Z
dc.date.available2021-11-23T10:02:09Z
dc.date.issued2019
dc.description.abstractThe aim was to provide global experts ranking on priorities in diagnostic tools for VAP in clinical practice. A multiple criteria decision analysis (MCDA) was performed to identify diagnosis tools for VAP diagnosis. Priority factors were identified after literature review. An international, multidisciplinary expert panel reviewed variables and ranked diagnostic tools. Experts from ten European hospitals participated. Regarding bedside clinical practices, seven required chest X-ray use in all patients, whereas six reported the use of blood cultures and endotracheal aspirate in all patients. Invasive techniques were routinely performed in seven sites. CRP, PCT, and Gram stains were performed in all patients by 5, 2, and 8, respectively. Impact on patient outcomes, safety, and impact on the decision to start antibiotic therapy were ranked as the top three relevant concerns (7.7/10, 7/10, and 6.9/10, respectively). Chest X-ray was ranked as the most important imaging technique to diagnose VAP (score 251.7). Apart from blood cultures, endotracheal aspirate culture was identified as the main collection method for the microbiological testing (scores of 274.8 and 246.8, respectively). Mini-BAL was the preferred invasive technique with a score of 208. Top three biomarkers were CRP (score 184.3), PCT (181.3), and WBC (166.4). Gram stain (192.5) was prioritized among laboratory diagnostic techniques. Using MCDA, it is recommended to perform a combination of diagnostic techniques including images (chest X-ray), culture of clinical specimens (blood cultures and endotracheal aspirate), and biomarkers (CRP or PCT) for VAP diagnosis at the bedside. Gram stain was ranked as the preferred laboratory technique.pt_PT
dc.description.versioninfo:eu-repo/semantics/publishedVersionpt_PT
dc.identifier.citationFerreira-Coimbra J, Ardanuy C, Diaz E, et al. Ventilator-associated pneumonia diagnosis: a prioritization exercise based on multi-criteria decision analysis. Eur J Clin Microbiol Infect Dis. 2020;39(2):281-286. doi:10.1007/s10096-019-03720-xpt_PT
dc.identifier.doi10.1007/s10096-019-03720-xpt_PT
dc.identifier.issn0934-9723
dc.identifier.issn1435-4373
dc.identifier.urihttp://hdl.handle.net/10400.16/2605
dc.language.isoengpt_PT
dc.peerreviewedyespt_PT
dc.publisherSpringerpt_PT
dc.relation.publisherversionhttps://link.springer.com/article/10.1007%2Fs10096-019-03720-xpt_PT
dc.subjectBiomarkerspt_PT
dc.subjectDiagnosispt_PT
dc.subjectImagingpt_PT
dc.subjectMCDApt_PT
dc.subjectMicrobiology diagnosispt_PT
dc.subjectMulticriteria decision analysispt_PT
dc.subjectVAPpt_PT
dc.subjectVentilator-associated pneumoniapt_PT
dc.titleVentilator-associated pneumonia diagnosis: a prioritization exercise based on multi-criteria decision analysispt_PT
dc.typejournal article
dspace.entity.typePublication
oaire.citation.conferencePlaceGermanypt_PT
oaire.citation.endPage286pt_PT
oaire.citation.issue2pt_PT
oaire.citation.startPage281pt_PT
oaire.citation.titleEuropean Journal of Clinical Microbiology & Infectious Diseasespt_PT
oaire.citation.volume39pt_PT
person.familyNameFerreira Coimbra
person.givenNameJoão
person.identifier.orcid0000-0002-5855-8600
rcaap.rightsopenAccesspt_PT
rcaap.typearticlept_PT
relation.isAuthorOfPublicationcc1c9f3b-f81e-4494-a4f1-bbeb560463ba
relation.isAuthorOfPublication.latestForDiscoverycc1c9f3b-f81e-4494-a4f1-bbeb560463ba

Files

Original bundle
Now showing 1 - 1 of 1
Thumbnail Image
Name:
Ferreira-coimbra-2020-Ventilator-associated-pneumonia-dia.pdf
Size:
199.8 KB
Format:
Adobe Portable Document Format
Download

Collections

MED 1A - Artigos publicados em revistas indexadas na Pubmed/Medline