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Diagnosis of monoclonal gammopathy of renal significance

dc.contributor.authorCorreia, S.
dc.contributor.authorSantos, S.
dc.contributor.authorMartins, L.
dc.contributor.authorSantos, J.
dc.date.accessioned2018-10-30T13:25:59Z
dc.date.available2018-10-30T13:25:59Z
dc.date.issued2018
dc.description.abstractMonoclonal gammopathies are a heterogeneous group of disorders characterized by clonal proliferation of immunoglobulin produced by B-lymphocytes or plasma cell clone. The term monoclonal gammopathy of renal significance (MGRS) was introduced to distinguish monoclonal gammopathies that result in the development of kidney disease from those that are benign. Screening for monoclonal immunoglobulin and an appropriate hematologic workup are fundamental and sometimes a difficult challenge, with therapeutic and prognostic implications. Kidney biopsy is essential to determine the exact nature of the lesion and to evaluate the severity of renal disease. In this review we discuss the clinical and pathologic features of MGRS, highlighting the most diagnostic difficulties and current therapeutic options.pt_PT
dc.description.versioninfo:eu-repo/semantics/publishedVersionpt_PT
dc.identifier.citationPort J Nephrol Hypert 2018; 32(1): 52-56pt_PT
dc.identifier.issn2183-1289
dc.identifier.urihttp://hdl.handle.net/10400.16/2248
dc.language.isoengpt_PT
dc.peerreviewedyespt_PT
dc.publisherSociedade Portuguesa de Nefrologiapt_PT
dc.relation.publisherversionhttp://www.spnefro.pt/rpnh/browse_all_issues/67_volume_32_number_1pt_PT
dc.subjectMonoclonal gammopathy of renal significancept_PT
dc.subjectM proteinpt_PT
dc.subjectRenal pathologypt_PT
dc.subjectTreatment.pt_PT
dc.titleDiagnosis of monoclonal gammopathy of renal significancept_PT
dc.typejournal article
dspace.entity.typePublication
oaire.citation.conferencePlacePortugalpt_PT
oaire.citation.endPage56pt_PT
oaire.citation.issue1pt_PT
oaire.citation.startPage52pt_PT
oaire.citation.titlePortuguese Journal of Nephrology and Hypertensionpt_PT
oaire.citation.volume32pt_PT
rcaap.rightsopenAccesspt_PT
rcaap.typearticlept_PT

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