Repository logo
 
Publication

Phakic Intraocular Lens Implantation After Deep Anterior Lamellar Keratoplasty: Retrospective Case Series Analysis With Long-Term Follow-Up

2019Journal article Open access
Simple item page
dc.contributor.authorMalheiro, Luisa
dc.contributor.authorCoelho, João
dc.contributor.authorNeves, Miguel Mesquita
dc.contributor.authorGomes, Miguel
dc.contributor.authorOLIVEIRA, LUIS
dc.date.accessioned2020-05-06T23:00:03Z
dc.date.available2020-05-06T23:00:03Z
dc.date.issued2019
dc.description.abstractPurpose: To report outcomes of phakic intraocular lens (IOL) implantation after deep anterior lamellar keratoplasty (DALK) to correct high ametropia. Setting: Centro Hospitalar Universitário do Porto, Portugal. Methods: Retrospective case series with 11 eyes submitted to phakic IOL implantation after DALK. Main outcomes measured were uncorrected and corrected distance visual acuity (UDVA and CDVA), refractive error components, tomographic parameters and endothelial cell density (ECD). The minimum follow-up was 3 years for all cases. Results: Mean ECD loss was 8.7±6.7% at 1 year, 13.1±8.6% at 3 years (n=11; p=0.016, p=0.007, respectively) and 14.0±20.4% at 5 years (n=5, p=0.212). Mean logMAR UDVA increased from 1.27±0.90logMAR preoperatively to 0.16±0.15logMAR postoperatively (p≤0.001) and no statistically significant differences were registered during follow-up. All patients gained at least 5 lines of UDVA. 54.5% of the eyes gained 1 line in CDVA postoperative and only one eye lost one CDVA line through follow-up. Efficacy and safety indexes at 1 and 3 years were 1.01-0.97 and 1.24-1.21, respectively. Mean spherical equivalent was reduced from -7.84±4.63 D preoperatively to -1.05±1.07 D postoperatively (p=0.001). Mean percentage of reduction in refractive cylinder and spherical error was 83.8±15.8% and 73.1±31.5%, respectively, p≤0.001 for both. In one eye there was a significantly gradual ECD loss over 5 years follow-up and the patient will be submitted to IOL explant. Conclusion: Phakic IOLs were effective for correction high ametropia after DALK, showing high efficacy and safety indexes with stability over time. However, it was registered a continuing endothelial cell loss postoperatively, which assumed to be higher than those reported in eyes without DALK.pt_PT
dc.description.versioninfo:eu-repo/semantics/publishedVersionpt_PT
dc.identifier.citationMalheiro L, Coelho J, Neves MM, Gomes M, Oliveira L. Phakic Intraocular Lens Implantation After Deep Anterior Lamellar Keratoplasty: Retrospective Case Series Analysis With Long-Term Follow-Up. Clin Ophthalmol. 2019;13:2043‐2052. Published 2019 Oct 17. doi:10.2147/OPTH.S202054pt_PT
dc.identifier.doi10.2147/OPTH.S202054pt_PT
dc.identifier.issn1177-5483
dc.identifier.issn1177-5467
dc.identifier.urihttp://hdl.handle.net/10400.16/2371
dc.language.isoengpt_PT
dc.peerreviewedyespt_PT
dc.publisherDove Medical Presspt_PT
dc.relation.publisherversionhttps://www.dovepress.com/phakic-intraocular-lens-implantation-after-deep-anterior-lamellar-kera-peer-reviewed-article-OPTHpt_PT
dc.rights.urihttp://creativecommons.org/licenses/by-nc/4.0/pt_PT
dc.subjectdeep anterior lamellar keratoplastypt_PT
dc.subjectendothelial cell densitypt_PT
dc.subjectphakic intraocular lenspt_PT
dc.subjectrefractive outcomespt_PT
dc.subjectvisual outcomespt_PT
dc.titlePhakic Intraocular Lens Implantation After Deep Anterior Lamellar Keratoplasty: Retrospective Case Series Analysis With Long-Term Follow-Uppt_PT
dc.typejournal article
dspace.entity.typePublication
oaire.citation.conferencePlaceNew Zealandpt_PT
oaire.citation.endPage2052pt_PT
oaire.citation.startPage2043pt_PT
oaire.citation.titleClinical ophthalmology (Auckland, N.Z.)pt_PT
oaire.citation.volume13pt_PT
person.familyNameMalheiro
person.familyNameCoelho
person.familyNameNeves
person.familyNameGomes
person.familyNameOLIVEIRA
person.givenNameLuisa
person.givenNameJoão
person.givenNameMiguel Mesquita
person.givenNameMiguel
person.givenNameLUIS
person.identifier.orcid0000-0001-9937-6806
person.identifier.orcid0000-0003-2261-5682
person.identifier.orcid0000-0002-3080-6035
person.identifier.orcid0000-0002-2198-7444
person.identifier.orcid0000-0001-7532-5991
rcaap.rightsopenAccesspt_PT
rcaap.typearticlept_PT
relation.isAuthorOfPublication786469ad-6b28-478e-b7b5-5e4cde542164
relation.isAuthorOfPublication9d2244b9-b054-46ab-8d35-d0a369849715
relation.isAuthorOfPublicationaa6920e7-d5c0-4d23-bd10-42317041c3e8
relation.isAuthorOfPublicationd80c68f2-4ad1-4abb-8cd7-3b8572857cc7
relation.isAuthorOfPublication68e21a43-a73d-4b4e-9255-09d9b601b55e
relation.isAuthorOfPublication.latestForDiscovery786469ad-6b28-478e-b7b5-5e4cde542164

Files

Original bundle
Now showing 1 - 1 of 1
Thumbnail Image
Name:
Phakic Intraocular Lens Implantation.pdf
Size:
2.52 MB
Format:
Adobe Portable Document Format
Download

Collections

SOFT - Artigos publicados em revistas indexadas na Pubmed/Medline