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Hospitalization Costs Due to Hypoglycemia in Patients with Diabetes: A Microcosting Approach

2020Journal article Open access
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dc.contributor.authorFerreira, João P.
dc.contributor.authorAraújo, Francisco
dc.contributor.authorDores, Jorge
dc.contributor.authorSantos, Lèlita
dc.contributor.authorPape, Estevão
dc.contributor.authorReis, Mónica
dc.contributor.authorChipepo, Árcia
dc.contributor.authorNascimento, Edite
dc.contributor.authorBaptista, Ana
dc.contributor.authorPires, Vanessa
dc.contributor.authorMarques, Carlos
dc.contributor.authorLages, Adriana S.
dc.contributor.authorConceição, João
dc.contributor.authorLaires, Pedro A.
dc.contributor.authorPelicano-Romano, João
dc.contributor.authorAlão, Sílvia
dc.date.accessioned2021-11-22T11:32:49Z
dc.date.available2021-11-22T11:32:49Z
dc.date.issued2020
dc.description.abstractIntroduction: Hypoglycemia leading to hospitalization is associated with adverse economic outcomes, although the real burden is unknown. The HIPOS-WARD (Hypoglycemia In Portugal Observational Study-Ward) aimed to characterize ward admissions due to hypoglycemia episodes in treated patients with diabetes and assess their economic impact to the National Health System. Methods: Observational, cross-sectional study, conducted in 16 Portuguese centers for 22 months. The applied microcosting approach was based on healthcare resource data, collected from patients' charts upon ward admission until discharge, and unitary costs from official/public data sources. Absenteeism was also estimated for active workers on the basis of the human capital approach. Results: Of the 176 patients with diabetes mellitus enrolled, 86% had type 2 diabetes. Half of the patients (50.0%) were on insulin-based therapy, followed by 30.1% on a secretagogue-based regimen, 9.7% on non-secretagogue therapy, and 10.2% on a combination of insulin and secretagogue. Overall mean costs per patient were medication, 45.45 €; laboratory analysis, 218.14 €; examinations, 64.91 €; physician and nurse time, 268.55 € and 673.39 €, respectively. Bed occupancy was the main cost driver (772.09 €) and indirect cost averaged 140.44 €. Overall, the cost per hypoglycemia episode leading to hospitalization averaged 2042.52 € (range 194.76-16,762.87 €). Patients treated with insulin-based regimens (2267.76 €) and type 2 diabetes (2051.29 €) had the highest mean costs. The mean cost increased with repeated hypoglycemic events (2191.67 €), correlated complications (2109.26 €), and death (5253.38 €). Conclusion: HIPOS-WARD's findings confirm and support both the substantial clinical and economic impact of hospitalization due to hypoglycemia in Portugal.pt_PT
dc.description.versioninfo:eu-repo/semantics/publishedVersionpt_PT
dc.identifier.citationFerreira JP, Araújo F, Dores J, et al. Hospitalization Costs Due to Hypoglycemia in Patients with Diabetes: A Microcosting Approach. Diabetes Ther. 2020;11(10):2237-2255. doi:10.1007/s13300-020-00868-0pt_PT
dc.identifier.doi10.1007/s13300-020-00868-0pt_PT
dc.identifier.issn1869-6961
dc.identifier.issn1869-6953
dc.identifier.urihttp://hdl.handle.net/10400.16/2583
dc.language.isoengpt_PT
dc.peerreviewedyespt_PT
dc.publisherSpringer Healthcarept_PT
dc.relation.publisherversionhttps://link.springer.com/article/10.1007%2Fs13300-020-00868-0pt_PT
dc.rights.urihttp://creativecommons.org/licenses/by-nc/4.0/pt_PT
dc.subjectCost studypt_PT
dc.subjectDiabetes mellituspt_PT
dc.titleHospitalization Costs Due to Hypoglycemia in Patients with Diabetes: A Microcosting Approachpt_PT
dc.typejournal article
dspace.entity.typePublication
oaire.citation.conferencePlaceUnited States of Americapt_PT
oaire.citation.endPage2255pt_PT
oaire.citation.issue10pt_PT
oaire.citation.startPage2237pt_PT
oaire.citation.titleDiabetes Therapypt_PT
oaire.citation.volume11pt_PT
person.familyNameDores
person.givenNameJorge
person.identifier.orcid0000-0001-9883-3809
person.identifier.scopus-author-id6508177324
rcaap.rightsopenAccesspt_PT
rcaap.typearticlept_PT
relation.isAuthorOfPublication4c215b73-6e1f-4d00-80ec-1ab674b7e89a
relation.isAuthorOfPublication.latestForDiscovery4c215b73-6e1f-4d00-80ec-1ab674b7e89a

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