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Amiodarone-Induced Electrical Storm: A Nightmare in the Emergency Room

2023-11Journal article Open access
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dc.contributor.authorCampinas, Andreia
dc.contributor.authorPereira Santos, Mariana
dc.contributor.authorSousa, Maria João
dc.contributor.authorGomes, Catarina
dc.contributor.authorTorres, Severo
dc.date.accessioned2024-06-17T14:55:51Z
dc.date.available2024-06-17T14:55:51Z
dc.date.issued2023-11
dc.description.abstractDrug-induced long QT syndrome (LQTS) is defined as prolonged corrected QT interval (QTc ≥460 ms) plus polymorphic ventricular arrhythmia fitting the description of torsades de pointes temporally associated with the administration of a drug or combination of drugs. Amiodarone therapy is a known uncommon cause of acquired QT interval prolongation that should not be underestimated. We present a case of an iatrogenic electrical storm with atrial fibrillation (AF) in which amiodarone was administered to attempt chemical cardioversion, resulting in an unnoticed prolongation of the QT interval, with subsequent repeated polymorphic ventricular tachycardia, managed with isoproterenol. Concomitant drugs and slight electrolyte disturbances potentiated this phenomenon. Given the widespread use of this drug in the emergency department, our case highlights a pertinent matter for all medical emergency practitioners. Additionally, it stresses the significance of potential precipitating factors, such as electrolyte imbalances, which are clinical conditions very frequent in the emergency context, along with the importance of recognizing drug interactions. Finally, this case also emphasizes the vital importance of closely monitoring the patient's receiving amiodarone.pt_PT
dc.description.versioninfo:eu-repo/semantics/publishedVersionpt_PT
dc.identifier.citationCampinas A, Pereira Santos M, Sousa MJ, Gomes C, Torres S. Amiodarone-Induced Electrical Storm: A Nightmare in the Emergency Room. Cureus. 2023;15(11):e49494. doi:10.7759/cureus.49494pt_PT
dc.identifier.doi10.7759/cureus.49494pt_PT
dc.identifier.issn2168-8184
dc.identifier.urihttp://hdl.handle.net/10400.16/2930
dc.language.isoengpt_PT
dc.peerreviewedyespt_PT
dc.publisherCureus, Inc.pt_PT
dc.relation.publisherversionhttps://www.cureus.com/articles/207561-amiodarone-induced-electrical-storm-a-nightmare-in-the-emergency-room#!/pt_PT
dc.rights.urihttp://creativecommons.org/licenses/by/4.0/pt_PT
dc.subjectdrug-induced long qt syndromept_PT
dc.subjectelectrical stormpt_PT
dc.subjectiatrogenic eventpt_PT
dc.subjectside effects of amiodaronept_PT
dc.subjecttorsa des pointespt_PT
dc.titleAmiodarone-Induced Electrical Storm: A Nightmare in the Emergency Roompt_PT
dc.typejournal article
dspace.entity.typePublication
oaire.citation.conferencePlaceUnited States of Americapt_PT
oaire.citation.issue11pt_PT
oaire.citation.startPagee49494pt_PT
oaire.citation.titleCureuspt_PT
oaire.citation.volume15pt_PT
person.familyNameCampinas
person.familyNamePereira Santos
person.familyNameSousa
person.familyNameTorres
person.givenNameAndreia
person.givenNameMariana
person.givenNameMaria João
person.givenNameSevero
person.identifier.ciencia-id931F-151B-1C03
person.identifier.ciencia-id3117-5106-43BC
person.identifier.orcid0000-0002-5662-8433
person.identifier.orcid0000-0001-8745-1557
person.identifier.orcid0000-0002-7662-4552
person.identifier.orcid0000-0002-7785-6291
rcaap.rightsopenAccesspt_PT
rcaap.typearticlept_PT
relation.isAuthorOfPublicationc3183d9e-e374-4d5a-aa43-b94e7ea204e2
relation.isAuthorOfPublicationeb1b7246-103c-4188-9b81-8861588d8251
relation.isAuthorOfPublication1cbe0cc7-e2e1-4269-93dc-52b2fcb942f3
relation.isAuthorOfPublicationa54a530e-1f4b-46fa-a69b-8207afcb0fd0
relation.isAuthorOfPublication.latestForDiscovery1cbe0cc7-e2e1-4269-93dc-52b2fcb942f3

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