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Bilateral proliferative retinopathy as the initial presentation of chronic myeloid leukemia.

2013Journal article Open access
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dc.contributor.authorMacedo, M.
dc.contributor.authorFigueiredo, A.
dc.contributor.authorFerreira, N.
dc.contributor.authorBarbosa, I.
dc.contributor.authorFurtado, M.
dc.contributor.authorCorreia, N.
dc.contributor.authorGomes, M.
dc.contributor.authorLume, M.
dc.contributor.authorMenéres, M.
dc.contributor.authorSantos, M.
dc.contributor.authorMeireles, M.
dc.date.accessioned2014-10-14T12:50:18Z
dc.date.available2014-10-14T12:50:18Z
dc.date.issued2013
dc.description.abstractThe authors report a rare case of a 48-year-old male with chronic myeloid leukemia (CML) who initially presented with a bilateral proliferative retinopathy. The patient complained of recent visual loss and floaters in both eyes (BE). Ophthalmologic evaluation revealed a best corrected visual acuity (BCVA) of 20/50 in the right eye and 20/200 in the left eye (LE). Fundoscopy showed the presence of bilateral peripheral capillary dropout with multiple retinal sea fan neovascularisations, which were confirmed on fluorescein angiography. Full blood count revealed hyperleukocytosis, thrombocytosis, anemia, and hyperuricemia. Bone marrow aspiration and biopsy showed the reciprocal chromosomal translocation t (9;22), diagnostic of CML. The patient was started on hydroxyurea, allopurinol and imatinib mesylate. He received bilateral panretinal laser photocoagulation and a vitrectomy was performed in the LE. The patient has been in complete hematologic, cytogenetic, and major molecular remission while on imatinib and his BCVA is 20/25 in BE.por
dc.identifier.citationMacedo MS, Figueiredo AR, Ferreira NN, Barbosa IM, Furtado MF, Correia NF, Gomes MP, Lume MR, Menéres MS, Santos MM, Meireles S M A. Bilateral proliferative retinopathy as the initial presentation of chronic myeloid leukemia.Middle East Afr J Ophthalmol 2013;20:353-356por
dc.identifier.doi10.4103/0974-9233.120016
dc.identifier.issn0974-9233
dc.identifier.urihttp://hdl.handle.net/10400.16/1691
dc.language.isoengpor
dc.peerreviewedyespor
dc.publisherMedknow Publications and Mediapor
dc.relation.publisherversionhttp://www.meajo.org/article.asp?issn=0974-9233;year=2013;volume=20;issue=4;spage=353;epage=356;aulast=Macedopor
dc.subjectChronic Myeloid Leukemiapor
dc.subjectHyperviscosity Syndromepor
dc.subjectProliferative Retinopathypor
dc.titleBilateral proliferative retinopathy as the initial presentation of chronic myeloid leukemia.por
dc.typejournal article
dspace.entity.typePublication
oaire.citation.conferencePlaceIndiapor
oaire.citation.endPage356por
oaire.citation.startPage353por
oaire.citation.titleMiddle East African journal of ophthalmologypor
oaire.citation.volume20(4)por
rcaap.rightsopenAccesspor
rcaap.typearticlepor

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