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Optical Coherence Tomography Findings (SD-OCT and OCTA) in Early-Stage Type 3 Neovascularization

2020Journal article Open access
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dc.contributor.authorSilva, Nisa
dc.contributor.authorMarta, Ana
dc.contributor.authorBaptista, Pedro
dc.contributor.authorFurtado, Maria João
dc.contributor.authorLume, Miguel
dc.date.accessioned2021-11-12T12:57:26Z
dc.date.available2021-11-12T12:57:26Z
dc.date.issued2020
dc.description.abstractA 76-year-old male presented with a small hyperreflective density in the outer nuclear layer with subtle retinal pigment epithelium (RPE) elevation and few intraretinal cysts on spectral-domain optical coherence tomography (SD-OCT). Optical coherence tomography angiography (OCTA) confirmed the presence of a tuft-shaped intraretinal neovascular lesion. SD-OCT performed 2 months before showed a smaller RPE elevation at the same location without intraretinal fluid. A 79-year-old male presented with a small hyperreflective density in the outer retina surrounded by scant intraretinal fluid on SD-OCT and a bright vessel on OCTA, suggesting early-stage type 3 neovascularization. SD-OCT performed 2 months before showed a smaller hyperreflectivity at the same location, without intraretinal fluid. An 84-year-old female presented with hyperreflective foci in the outer retina overlying a serous pigment epithelium detachment (PED) with focal RPE disruption on SD-OCT. SD-OCT performed 2 months before showed the same hyperreflective lesion associated with a shallower PED. No neovascular lesions were found on OCTA after six injections of bevacizumab. To conclude, careful evaluation of SD-OCT allows for early detection of type 3 neovascularization at a pre-exudative stage. OCTA may be useful in confirming the presence of intraretinal neovascular lesion and monitoring response to anti-vascular endothelial growth factor agents.pt_PT
dc.description.versioninfo:eu-repo/semantics/publishedVersionpt_PT
dc.identifier.citationSilva N, Marta A, Baptista P, Furtado MJ, Lume M. Optical Coherence Tomography Findings (SD-OCT and OCTA) in Early-Stage Type 3 Neovascularization. Case Rep Ophthalmol. 2020;11(2):493-499. Published 2020 Aug 19. doi:10.1159/000509139pt_PT
dc.identifier.doi10.1159/000509139pt_PT
dc.identifier.issn1663-2699
dc.identifier.urihttp://hdl.handle.net/10400.16/2539
dc.language.isoengpt_PT
dc.peerreviewedyespt_PT
dc.publisherKarger AGpt_PT
dc.relation.publisherversionhttps://www.karger.com/Article/FullText/509139pt_PT
dc.rights.urihttp://creativecommons.org/licenses/by-nc/4.0/pt_PT
dc.subjectAge-related macular degenerationpt_PT
dc.subjectEarly-stage type 3 macular neovascularizationpt_PT
dc.subjectOptical coherence tomographypt_PT
dc.titleOptical Coherence Tomography Findings (SD-OCT and OCTA) in Early-Stage Type 3 Neovascularizationpt_PT
dc.typejournal article
dspace.entity.typePublication
oaire.citation.conferencePlaceSwitzerlandpt_PT
oaire.citation.endPage499pt_PT
oaire.citation.issue2pt_PT
oaire.citation.startPage493pt_PT
oaire.citation.titleCase Reports in Ophthalmologypt_PT
oaire.citation.volume11pt_PT
person.familyNameMarta
person.givenNameAna
person.identifier.orcid0000-0003-3495-4649
rcaap.rightsopenAccesspt_PT
rcaap.typearticlept_PT
relation.isAuthorOfPublication27861687-928c-4618-9f11-92d74ec326e0
relation.isAuthorOfPublication.latestForDiscovery27861687-928c-4618-9f11-92d74ec326e0

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