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Effect of Aging in the Perception of Health-Related Quality of Life in End-Stage Renal Disease Patients under Online-Hemodiafiltration

dc.contributor.authorMoura, A.
dc.contributor.authorMadureira, J.
dc.contributor.authorAlija, P.
dc.contributor.authorFernandes, J.
dc.contributor.authorOliveira, .
dc.contributor.authorLopez, M.
dc.contributor.authorFilgueiras, M.
dc.contributor.authorAmado, L.
dc.contributor.authorSameiro-Faria, M.
dc.contributor.authorMiranda, V.
dc.contributor.authorSantos-Silva, A.
dc.contributor.authorCosta, E.
dc.date.accessioned2016-07-26T11:32:45Z
dc.date.available2016-07-26T11:32:45Z
dc.date.issued2015-02
dc.description.abstractThis work aimed to evaluate how aging could influence patients' perception of health quality of life (HRQOL), as well as, the effect of aging on dialysis adequacy and in hematological, iron status, inflammatory and nutritional markers. In this transversal study were enrolled 305 ESRD patients under online-hemodiafiltration (OL-HDF) (59.67% males; 64.9 ± 14.3 years old). Data about comorbidities, hematological data, iron status, dialysis adequacy, nutritional and inflammatory markers were collected from patient's records. Moreover, HRQOL score, by using the Kidney Disease Quality of Life-Short Form (KDQOL-SF), was assessed. Analyzing the results according to quartiles of age, significant differences were found for some parameters evaluated by the KDQOL-SF instrument, namely for work status, physical functioning and role-physical, which decreased with increasing age. We also found a higher proportion of diabetic patients, a decrease in creatinine, iron, albumin serum levels, transferrin saturation and nPCR, with increasing age. Moreover, significant negative correlations were found between age and mean cell hemoglobin concentration, iron, transferrin saturation, albumin, nPCR, work status, physical functioning and role-physical. In conclusion, our results showed that aging is associated with a decreased work status, physical functioning and role-physical, with a decreased dialysis adequacy, iron availability and nutritional status, and with an increased proportion of diabetic patients and of patients using central venous catheter, as the vascular access. The knowledge of these changes associated with aging, which have impact in the quality of life of the patients, could be useful in their management.pt_PT
dc.identifier.citationAging Dis. 2015;6(1):17-26pt_PT
dc.identifier.doi10.14336/AD.2014.0514pt_PT
dc.identifier.issn2152-5250
dc.identifier.urihttp://hdl.handle.net/10400.16/1970
dc.language.isoengpt_PT
dc.peerreviewedyespt_PT
dc.publisherJKL Internationalpt_PT
dc.relation.publisherversionhttp://www.ncbi.nlm.nih.gov/pmc/articles/PMC4306470/pdf/ad-6-1-17.pdfpt_PT
dc.subjectHealth-related quality of lifept_PT
dc.subjectagingpt_PT
dc.subjectdialysis adequacy;pt_PT
dc.subjectiron availabilitypt_PT
dc.subjectnutritional statuspt_PT
dc.subjecton-line hemodiafiltrationpt_PT
dc.subjectgenderpt_PT
dc.titleEffect of Aging in the Perception of Health-Related Quality of Life in End-Stage Renal Disease Patients under Online-Hemodiafiltrationpt_PT
dc.typejournal article
dspace.entity.typePublication
oaire.citation.conferencePlaceUnited States of Americapt_PT
oaire.citation.endPage26pt_PT
oaire.citation.issue1pt_PT
oaire.citation.startPage17pt_PT
oaire.citation.titleAging and Diseasept_PT
oaire.citation.volume6pt_PT
rcaap.rightsopenAccesspt_PT
rcaap.typearticlept_PT

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