Repository logo
 
Publication

Health-Related Quality of Life in Pulmonary Hypertension and Its Clinical Correlates: A Cross-Sectional Study

2018-03-19Journal article Open access
Simple item page
dc.contributor.authorReis, A.
dc.contributor.authorSantos, M.
dc.contributor.authorVicente, M.
dc.contributor.authorFurtado, I.
dc.contributor.authorCruz, C.
dc.contributor.authorMelo, A.
dc.contributor.authorCarvalho, L.
dc.contributor.authorGonçalves, F.
dc.contributor.authorSa-Couto, P.
dc.contributor.authorAlmeida, L.
dc.date.accessioned2019-07-15T15:09:17Z
dc.date.available2019-07-15T15:09:17Z
dc.date.issued2018-03-19
dc.description.abstractBACKGROUND: Health-related quality of life (HRQoL) impairment is common in pulmonary hypertension (PH), but its clinical predictors are not well established. This study aims to characterize the HRQoL of patients with pulmonary arterial hypertension (PAH) and other precapillary forms of PH (pcPH) and to explore its clinical correlates. MATERIALS AND METHODS: A cross-sectional, observational study of patients with documented PAH and other forms of pcPH. Patients completed two patient-reported outcome measures (PROM): Cambridge Pulmonary Hypertension Outcome Review (CAMPHOR) and Nottingham Health Profile (NHP). Clinical characteristics were retrieved from electronic medical records. RESULTS: Mean CAMPHOR and NHP scores for the study population were indicative of a moderate HRQoL impairment. Patients in World Health Organisation Functional Classes (WHO FC) III/IV showed significantly worse HRQoL. The main clinical correlates of HRQoL were WHO FC, 6-minute walking distance (6MWD), and Borg dyspnoea index. Overall quality of life (QoL), assessed through CAMPHOR's QoL domain, showed patterns comparable to HRQoL measured by both instruments. CONCLUSIONS: HRQoL, measured by two different PROMs, is impaired in Portuguese patients with PAH and other forms of pcPH, particularly in patients with increased disease severity. WHO FC, 6MWD, and Borg dyspnoea index are highly correlated with HRQoL and QoL.pt_PT
dc.description.versioninfo:eu-repo/semantics/publishedVersionpt_PT
dc.identifier.citationBiomed Res Int. 2018 Mar 19;2018:3924517pt_PT
dc.identifier.doi10.1155/2018/3924517pt_PT
dc.identifier.issn2314-6141
dc.identifier.issn2314-6133
dc.identifier.urihttp://hdl.handle.net/10400.16/2267
dc.language.isoengpt_PT
dc.peerreviewedyespt_PT
dc.publisherHindawipt_PT
dc.relation.publisherversionhttps://www.hindawi.com/journals/bmri/2018/3924517/pt_PT
dc.subjectCross-Sectional Studiespt_PT
dc.subjectDyspneapt_PT
dc.subjectFemalept_PT
dc.subjectHealth Statuspt_PT
dc.subjectHumanspt_PT
dc.subjectHypertension, Pulmonarypt_PT
dc.subjectMalept_PT
dc.subjectMiddle Agedpt_PT
dc.subjectQuality of Lifept_PT
dc.subjectSurveys and Questionnairespt_PT
dc.titleHealth-Related Quality of Life in Pulmonary Hypertension and Its Clinical Correlates: A Cross-Sectional Studypt_PT
dc.typejournal article
dspace.entity.typePublication
oaire.citation.conferencePlaceUnited States of Americapt_PT
oaire.citation.endPage10pt_PT
oaire.citation.startPage3924517pt_PT
oaire.citation.titleBioMed Research Internationalpt_PT
oaire.citation.volume2018pt_PT
person.familyNameReis
person.familyNameSantos
person.givenNameAbílio
person.givenNameMario
person.identifier.ciencia-idCB17-AD56-DE37
person.identifier.orcid0000-0003-4976-3781
person.identifier.orcid0000-0002-4509-0260
rcaap.rightsopenAccesspt_PT
rcaap.typearticlept_PT
relation.isAuthorOfPublication70cee3ac-8f7d-414e-828f-192f71534714
relation.isAuthorOfPublication7cf7a05b-3af4-4eaf-b3b5-9021cb7a2629
relation.isAuthorOfPublication.latestForDiscovery70cee3ac-8f7d-414e-828f-192f71534714

Files

Original bundle
Now showing 1 - 1 of 1
Thumbnail Image
Name:
Health-Related Quality of Life in Pulmonary Hypertension.pdf
Size:
1.55 MB
Format:
Adobe Portable Document Format
Download
License bundle
Now showing 1 - 1 of 1
No Thumbnail Available
Name:
license.txt
Size:
1.35 KB
Format:
Item-specific license agreed upon to submission
Description:
Download

Collections

MED 1A - Artigos publicados em revistas indexadas na Pubmed/Medline