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Publication
Caso electroencefalográfico: Panencefalite Esclerosante Subaguda (pós-sarampo)
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Advisor(s)
Abstract(s)
ABSTRACT
Introduction: Subacute sclerosing panencephalitis is a very
rare disease in countries with measles vaccination programs, and
is due to a persistent infection by a defective measles virus. The
disease has a progressive fatal course.
Case report: We describe the case of a 13 year-old boy
with a progressive clinical picture of cognitive impairment, myoclonus,
and pyramidal, extrapyramidal and cerebellar signs. The
diagnosis was based upon clinical manifestations, the presence
of characteristic periodic EEG discharges, and the demonstration
of raised antibody titres against measles in the plasma and
cerebrospinal fluid.
Conclusions: Diagnosis of subacute sclerosing panencephalitis
is based on clinical suspicion, very characteristic electroencephalographic
abnormalities (typical periodic complexes)
and raised antibodies to measles virus in the cerebrospinal fluid.
It seldom occurs in patients with immunisation against measles,
except in those with early onset of measles.
Description
Keywords
Subacute sclerosing panencephalitis electroencephalogram periodic complexes measles virus
Citation
Nascer e Crescer 2011; 20(1): 49-50