Repository logo
 
Publication

Inclusion Body Myositis Treated with Alemtuzumab

2019Journal article Open access
Simple item page
dc.contributor.authorSá, J.
dc.contributor.authorCostelha, J.
dc.contributor.authorMarinho, António
dc.date.accessioned2020-05-12T09:18:17Z
dc.date.available2020-05-12T09:18:17Z
dc.date.issued2019
dc.description.abstractnclusion body myositis (IBM) is a chronic inflammatory myopathy with a progressive course. It is more common in the later years of life and usually presents with limb weakness. We present the case of a patient who developed proximal weakness in the lower limbs and, four years later, facial asymmetry. Blood analysis revealed high lactate dehydrogenase and creatinine kinase values. The diagnosis was obtained through muscle biopsy which met the histological criteria for IBM. The patient started treatment with alemtuzumab, leading to stabilisation of the symptoms in two years. Learning points: IBM should be considered in the differential diagnosis of muscle weakness.Patients may present uncommon symptoms, such as prominent facial involvement.Alemtuzumab may potentially be beneficial in limiting the progression of IBM.pt_PT
dc.description.versioninfo:eu-repo/semantics/publishedVersionpt_PT
dc.identifier.citationSá J, Costelha J, Marinho A. Inclusion Body Myositis Treated with Alemtuzumab. Eur J Case Rep Intern Med. 2019;6(12):001368. Published 2019 Dec 12. doi:10.12890/2019_001368pt_PT
dc.identifier.doi10.12890/2019_001368pt_PT
dc.identifier.issn2284-2594
dc.identifier.urihttp://hdl.handle.net/10400.16/2377
dc.language.isoengpt_PT
dc.peerreviewedyespt_PT
dc.publisherSMC Mediapt_PT
dc.relation.publisherversionhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC6936915/pdf/1368-1-10393-3-10-20191203.pdfpt_PT
dc.rights.urihttp://creativecommons.org/licenses/by-nc-nd/4.0/pt_PT
dc.subjectInclusion body myositispt_PT
dc.subjectalemtuzumabpt_PT
dc.subjectmyopathypt_PT
dc.subjecttreatmentpt_PT
dc.titleInclusion Body Myositis Treated with Alemtuzumabpt_PT
dc.typejournal article
dspace.entity.typePublication
oaire.citation.conferencePlaceItalypt_PT
oaire.citation.issue12pt_PT
oaire.citation.startPage001368pt_PT
oaire.citation.titleEuropean journal of case reports in internal medicinept_PT
oaire.citation.volume6pt_PT
person.familyNameMarinho
person.givenNameAntónio
person.identifier.ciencia-id071D-2A63-84A4
person.identifier.orcid0000-0002-3295-6723
person.identifier.scopus-author-id7004241740
rcaap.rightsopenAccesspt_PT
rcaap.typearticlept_PT
relation.isAuthorOfPublication4f283ec3-446f-4a55-8451-207d4c4fe994
relation.isAuthorOfPublication.latestForDiscovery4f283ec3-446f-4a55-8451-207d4c4fe994

Files

Original bundle
Now showing 1 - 1 of 1
Thumbnail Image
Name:
Inclusion Body Myositis Treated With Alemtuzumab.pdf
Size:
167.85 KB
Format:
Adobe Portable Document Format
Download

Collections

UIC - Artigos publicados em revistas indexadas na Medline