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Tacrolimus, a forgotten agent in kidney transplant leukopenia

dc.contributor.authorAzevedo, P.
dc.contributor.authorFreitas, C.
dc.contributor.authorSilva, H.
dc.contributor.authorAguiar, P.
dc.contributor.authorSantos, T.
dc.contributor.authorCabral, J.
dc.contributor.authorRocha, G.
dc.contributor.authorAlmeida, M.
dc.contributor.authorPedroso, S.
dc.contributor.authorMartins, L.
dc.contributor.authorDias, L.
dc.contributor.authorCastro-Henriques, A.
dc.contributor.authorCabrita, A.
dc.date.accessioned2013-12-26T18:28:55Z
dc.date.available2013-12-26T18:28:55Z
dc.date.issued2013
dc.description.abstractLeukopenia in kidney transplant patients is frequent, it causes potentially life-threatening complications, but it is often poorly characterized. Opportunistic infections, immunologic disturbances and drug-related toxicity are principal causes of single or multilineage cytopenias. Tacrolimus-induced leukopenia is a less recognized but frequent complication. We describe one patient with leukopenia developing within seven months after renal transplant. After excluding other potential causes, tacrolimus was switched to cyclosporine, with recovery of white blood cell count. Based on the clinical report, the authors reviewed causes of post-transplant leukopenia, focusing on the diagnostic investigation. Early diagnosis and interventions are fundamental to improve prognosis.por
dc.identifier.citationPort J Nephrol Hypert 2013; 27(1): 55-60por
dc.identifier.issn2183-1289
dc.identifier.urihttp://hdl.handle.net/10400.16/1546
dc.language.isoengpor
dc.peerreviewedyespor
dc.publisherSociedade Portuguesa de Nefrologiapor
dc.relation.publisherversionhttp://www.spnefro.pt/RPNH/PDFs/n1_2013/artigo_09.pdfpor
dc.subjectLeukopeniapor
dc.subjectrenal transplantationpor
dc.subjecttacrolimuspor
dc.titleTacrolimus, a forgotten agent in kidney transplant leukopeniapor
dc.typejournal article
dspace.entity.typePublication
oaire.citation.conferencePlacePortugalpor
oaire.citation.endPage60por
oaire.citation.issue1por
oaire.citation.startPage55por
oaire.citation.titlePortuguese Journal of Nephrology Hypertensionpor
oaire.citation.volume27por
rcaap.rightsopenAccesspor
rcaap.typearticlepor

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