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Advisor(s)
Abstract(s)
Temporary transfer to hemodialysis, as a peritoneal
rest, may be a rescue therapy to recover ultrafiltration
(UF) in patients who develop peritoneal hyperpermeability
as a complication of continuous
ambulatory peritoneal dialysis (CAPD). However,
peritoneal sclerosis has been reported after peritoneal
pause.
Since the beginning of our CAPD program in
1985, 12°elective peritoneal pauses have been performed
in 11°patients who developed type°I ultrafiltration
failure (D/P240 creatinine: 0.88°± 0.09) after
42°± 14°months on CAPD. Eight patients recovered
UF and remained on CAPD with standard solutions
for 10°± 9°months more (minimum: 5°months; maximum:
29°months). Only 3 of those patients were later
switched to hemodialysis because of recurring UF
failure. One patient remains on CAPD (62°months of
follow-up). Four patients failed to respond and were
permanently transferred to hemodialysis, without signs
of developing encapsulating peritoneal sclerosis. The
failed pauses were performed later after the detection
of UF failure than were the successful ones (483°±
574°days vs. 54°± 52°days).
In our study, 8 of 12 peritoneal pauses (66.6%)
successfully treated type°I UF failure and prolonged
CAPD retention. If a pause is initiated soon after diagnosis
of UF failure, results may improve further.
We urge prospective studies to better determine the
best and timely therapeutic approach in patients with
loss of ultrafiltration.
Description
No pdf deste artigo (p. 78-80) estão integrados mais 3 artigos relacionados:(p. 68-71), (p. 72-74) e (p. 75-77)
Keywords
Peritoneal rest ultrafiltration failure peritoneal transport
Citation
Adv Perit Dial. 2002;18:78‐80. PMID: 12402593
Publisher
Peritoneal Dialysis Bulletin, Inc.