Publication
Selfâreported drug allergy in a general adult Portuguese population
| dc.contributor.author | GOMES, E. | |
| dc.contributor.author | CARDOSO, M.F. | |
| dc.contributor.author | PRAĂA, F. | |
| dc.contributor.author | GOMES, L. | |
| dc.contributor.author | MARIĂO, E. | |
| dc.contributor.author | DEMOLY, P. | |
| dc.date.accessioned | 2011-01-19T09:50:26Z | |
| dc.date.available | 2011-01-19T09:50:26Z | |
| dc.date.issued | 2004-09 | |
| dc.description.abstract | Clin Exp Allergy. 2004 Oct;34(10):1597-601. Self-reported drug allergy in a general adult Portuguese population. Gomes E, Cardoso MF, Praça F, Gomes L, Mariùo E, Demoly P. Serviço de Imunoalergologia, Hospital Maria Pia, Porto, Portugal. evamariasrg@yahoo.com Abstract AIM: To estimate the prevalence of self-reported drug allergy in adults. METHODS: Cross-sectional survey of a general adult population from Porto (all of whom were living with children involved in the International Study of Asthma and Allergies in Childhood-phase three), during the year 2002, using a self-administered questionnaire. RESULTS: The prevalence of self-reported drug allergy was 7.8% (181/2309): 4.5% to penicillins or other beta-lactams, 1.9% to aspirin or other non-steroidal anti-inflammatory drugs (NSAIDs) and 1.5% to other drugs. In the group 'allergic to beta-lactams', the most frequently implicated drug was penicillin G or V (76.2%) followed by the association of amoxicillin and clavulanic acids (14.3%). In the group 'allergic to NSAIDs', acetylsalicylic acid (18.2%) and ibuprofen (18.2%) were the most frequently identified drugs, followed by nimesulide and meloxicam. Identification of the exact name of the involved drug was possible in less than one-third of the patients, more often within the NSAID group (59.5%). Women were significantly more likely to claim a drug allergy than men (10.2% vs. 5.3%). The most common manifestations were cutaneous (63.5%), followed by cardiovascular symptoms (35.9%). Most of the reactions were immediate, occurring on the first day of treatment (78.5%). Only half of the patients were submitted to drug allergy investigations. The majority (86.8%) completely avoided the suspected culprit drug thereafter. CONCLUSIONS: The results showed that self-reported allergy to drugs is highly prevalent and poorly explored. Women seem to be more susceptible. beta-lactams and NSAIDs are the most frequently concerned drugs. PMID: 15479276 [PubMed - indexed for MEDLINE] | por |
| dc.identifier.issn | 0954-7894 | |
| dc.identifier.uri | http://hdl.handle.net/10400.16/511 | |
| dc.language.iso | eng | por |
| dc.peerreviewed | yes | por |
| dc.publisher | Wiley-Blackwell | por |
| dc.relation.publisherversion | http://onlinelibrary.wiley.com/doi/10.1111/j.1365-2222.2004.02070.x/abstract | por |
| dc.title | Selfâreported drug allergy in a general adult Portuguese population | por |
| dc.type | journal article | |
| dspace.entity.type | Publication | |
| oaire.citation.title | Clinical and Experimental Allergy | por |
| rcaap.rights | restrictedAccess | por |
| rcaap.type | article | por |