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Atypical Cogan’s Syndrome

dc.contributor.authorQueirós, J.
dc.contributor.authorMaia, S.
dc.contributor.authorSeca, M.
dc.contributor.authorFriande, A.
dc.contributor.authorAraújo, M.
dc.contributor.authorMeireles, A.
dc.date.accessioned2013-06-17T11:02:25Z
dc.date.available2013-06-17T11:02:25Z
dc.date.issued2013-04
dc.description.abstractBackground. Cogan's syndrome is a rare clinical entity whose etiopathology is still unknown, and the treatment strategies are not clearly defined. Case. A 23-year-old male presented with symptoms of headache, peripheral facial palsy, persistent right hearing loss and bilateral papillitis. Workup excluded all infectious, granulomatous, neoplastic, and immune causes. The diagnosis of atypical Cogan's syndrome was established, and the patient was treated with systemic corticosteroids and later on with cyclophosphamide and methotrexate. There were improvement of visual symptoms and stabilisation of left hearing. Conclusion. Cogan's syndrome is a very rare disease with no specific biological tests for the diagnosis. The diagnostic exams are mostly important to exclude other etiologies. The atypical ocular and audiovestibular manifestations make the diagnosis difficult, delaying the institution of appropriate therapy which may result in profound bilateral deafness.por
dc.identifier.citationCase Rep Ophthalmol Med. 2013;2013:476527.por
dc.identifier.issn2090-6730
dc.identifier.urihttp://hdl.handle.net/10400.16/1448
dc.language.isoengpor
dc.peerreviewedyespor
dc.publisherHindawi Publishing Corporationpor
dc.relation.publisherversionhttp://dx.doi.org/10.1155/2013/476527por
dc.titleAtypical Cogan’s Syndromepor
dc.typejournal article
dspace.entity.typePublication
oaire.citation.conferencePlaceUnited States of Americapor
oaire.citation.issueArticle ID 476527, 4 pagespor
oaire.citation.titleCase reports in ophthalmological medicinepor
oaire.citation.volume2013por
rcaap.rightsopenAccesspor
rcaap.typearticlepor

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