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Timely and Blood-Based Multiplex Molecular Profiling of Acute Stroke

2021-08Journal article Open access
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dc.contributor.authorDias, Alexandre
dc.contributor.authorSilva, Isabel
dc.contributor.authorPinto, Inês Mendes
dc.contributor.authorMaia, Luis
dc.date.accessioned2024-01-30T12:17:57Z
dc.date.available2024-01-30T12:17:57Z
dc.date.issued2021-08
dc.description.abstractStroke is a leading cause of death and disability in the world. To address such a problem, early diagnosis and tailored acute treatment represent one of the major priorities in acute stroke care. Since the efficacy of reperfusion treatments is highly time-dependent, there is a critical need to optimize procedures for faster and more precise diagnosis. We provide a concise review of the most relevant and well-documented blood-protein biomarkers that exhibit greater potential for translational to clinical practice in stroke differential diagnosis and to differentiate ischemic stroke from hemorrhagic stroke, followed by an overview of the most recent point-of-care technological approaches to address this problem. The integration of fluid-based biomarker profiling, using point-of-care biosensors with demographic, clinical, and neuroimaging parameters in multi-dimensional clinical decision-making algorithms, will be the next step in personalized stroke care.pt_PT
dc.description.versioninfo:eu-repo/semantics/publishedVersionpt_PT
dc.identifier.citationDias A, Silva I, Pinto IM, Maia LF. Timely and Blood-Based Multiplex Molecular Profiling of Acute Stroke. Life (Basel). 2021;11(8):816. doi:10.3390/life11080816pt_PT
dc.identifier.doi10.3390/life11080816pt_PT
dc.identifier.issn2075-1729
dc.identifier.urihttp://hdl.handle.net/10400.16/2905
dc.language.isoengpt_PT
dc.peerreviewedyespt_PT
dc.publisherMDPIpt_PT
dc.relation.publisherversionhttps://www.mdpi.com/2075-1729/11/8/816pt_PT
dc.rights.urihttp://creativecommons.org/licenses/by/4.0/pt_PT
dc.subjectPOC devicespt_PT
dc.subjectbiomarkerspt_PT
dc.subjectbiosensorspt_PT
dc.subjectbloodpt_PT
dc.subjectstrokept_PT
dc.titleTimely and Blood-Based Multiplex Molecular Profiling of Acute Strokept_PT
dc.typejournal article
dspace.entity.typePublication
oaire.citation.conferencePlaceSwitzerlandpt_PT
oaire.citation.issue8pt_PT
oaire.citation.startPage816pt_PT
oaire.citation.titleLifept_PT
oaire.citation.volume11pt_PT
person.familyNameDias
person.familyNameSilva
person.familyNameMaia
person.givenNameAlexandre
person.givenNameIsabel
person.givenNameLuis
person.identifier.ciencia-id751C-205E-5A80
person.identifier.ciencia-id9F1E-51AF-C38B
person.identifier.orcid0000-0002-5110-5764
person.identifier.orcid0000-0001-7244-4792
person.identifier.orcid0000-0002-8140-3471
person.identifier.ridK-9890-2014
person.identifier.ridJ-1742-2014
rcaap.rightsopenAccesspt_PT
rcaap.typearticlept_PT
relation.isAuthorOfPublication0992072b-3729-4525-a86f-c185063aa28b
relation.isAuthorOfPublicationb63c909d-b3f9-4507-bd37-99e7740ec2b1
relation.isAuthorOfPublication2b17a107-4559-498c-82f9-559a1ded4cac
relation.isAuthorOfPublication.latestForDiscoveryb63c909d-b3f9-4507-bd37-99e7740ec2b1

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