Repository logo
 
Publication

Predicting 6-Month Mortality in Incident Elderly Dialysis Patients: A Simple Prognostic Score

2020Journal article Open access
Simple item page
dc.contributor.authorLascasas, Josefina
dc.contributor.authorOliveira, Pedro
dc.contributor.authorJ, Malheiro
dc.contributor.authorCampos, Andreia
dc.contributor.authorCorreia, Sofia
dc.contributor.authorCabrita, Antonio
dc.contributor.authorLobato, Luísa
dc.contributor.authorFonseca, Isabel
dc.date.accessioned2022-03-22T15:10:52Z
dc.date.available2022-03-22T15:10:52Z
dc.date.issued2020
dc.description.abstractAim: Mortality in end-stage renal disease (ESRD) remains high, particularly among elderly, who represents the most rapidly growing segment of the ESRD population in wealthier countries. We developed and validated a risk score in elderly patients to predict 6-month mortality after dialysis initiation. Methods: We used data from a cohort of 421 patients, aged 65 years and over who started dialysis between 2009 and 2016, in our Nephrology department. The predictive score was developed using a multivariable logistic regression analysis. A bootstrapping technique was used for internal validation. Results: The overall mortality within 6 months was 14.0%. Five independent predictors were identified, and a points system was constructed: age 75 years or older (2 points), coronary artery disease (2), cerebrovascular disease with hemiplegia (2), time of nephrology care before dialysis (<3.0 months [2]; ≥3 to <12 months [1]), and serum albumin levels (3.0-3.49 g/dL [1]; <3.0 g/dL [2]). A score of 6 identified patients with a 70% risk of 6-month mortality. Model performance was good in both discrimination (area under the curve of 0.793; [95% CI 0.73-0.86]) and validation (concordance statistics of 0.791 [95% CI 0.73-0.85]). Conclusions: We developed a simple prediction score based on readily available clinical and laboratory data that can be a practical and useful tool to assess short-term prognosis in elderly patients starting dialysis. It may help to inform patients and their families about ESRD treatment options and provide a more patient-centered overall approach to care.pt_PT
dc.description.versioninfo:eu-repo/semantics/publishedVersionpt_PT
dc.identifier.citationSantos J, Oliveira P, Malheiro J, et al. Predicting 6-Month Mortality in Incident Elderly Dialysis Patients: A Simple Prognostic Score. Kidney Blood Press Res. 2020;45(1):38-50. doi:10.1159/000504136pt_PT
dc.identifier.doi10.1159/000504136pt_PT
dc.identifier.issn1420-4096
dc.identifier.issn1423-0143
dc.identifier.urihttp://hdl.handle.net/10400.16/2676
dc.language.isoengpt_PT
dc.peerreviewedyespt_PT
dc.publisherKargerpt_PT
dc.relation.publisherversionhttps://www.karger.com/Article/FullText/504136pt_PT
dc.rights.urihttp://creativecommons.org/licenses/by-nc-nd/4.0/pt_PT
dc.subjectDialysispt_PT
dc.subjectElderlypt_PT
dc.subjectEnd-stage renal diseasept_PT
dc.subjectPrognosis scorept_PT
dc.subjectShared decision makingpt_PT
dc.titlePredicting 6-Month Mortality in Incident Elderly Dialysis Patients: A Simple Prognostic Scorept_PT
dc.typejournal article
dspace.entity.typePublication
oaire.citation.conferencePlaceSwitzerlandpt_PT
oaire.citation.endPage50pt_PT
oaire.citation.issue1pt_PT
oaire.citation.startPage38pt_PT
oaire.citation.titleKidney and Blood Pressure Researchpt_PT
oaire.citation.volume45pt_PT
person.familyNameSousa Santos Lascasas
person.familyNameMalheiro
person.familyNameCampos
person.familyNameCorreia
person.familyNameCabrita
person.familyNameCorreia Lopes Lobato
person.familyNameFonseca
person.givenNameJosefina Maria
person.givenNameJorge
person.givenNameAndreia
person.givenNameSofia
person.givenNameAntonio
person.givenNameLuísa Maria
person.givenNameIsabel
person.identifier415128
person.identifier.ciencia-idD218-B3AB-719D
person.identifier.ciencia-idB61E-6079-8F82
person.identifier.ciencia-id6716-A5D1-FB3F
person.identifier.orcid0000-0003-0383-4994
person.identifier.orcid0000-0002-9625-5889
person.identifier.orcid0000-0003-0062-5732
person.identifier.orcid0000-0001-5025-1658
person.identifier.orcid0000-0003-3794-9239
person.identifier.orcid0000-0002-1464-083X
person.identifier.orcid0000-0001-8984-1751
person.identifier.ridK-6320-2013
person.identifier.ridK-6339-2013
person.identifier.scopus-author-id26434404600
person.identifier.scopus-author-id57211840457
person.identifier.scopus-author-id55941495000
rcaap.rightsopenAccesspt_PT
rcaap.typearticlept_PT
relation.isAuthorOfPublication98f055b6-738c-41c4-83c1-ffcfe6d6b33b
relation.isAuthorOfPublicationbf3e5709-4eaa-49d7-bbd9-20e9cfe84979
relation.isAuthorOfPublication265cbb13-b6f7-4030-b6fe-eb9b40306f8b
relation.isAuthorOfPublicationdbcc1fe0-e968-41f6-96ea-102866e84cb5
relation.isAuthorOfPublicatione6585113-b703-4899-ab35-2dfd11593588
relation.isAuthorOfPublication6ccdc530-edc9-4488-9501-ffd1557573e3
relation.isAuthorOfPublication2c7a2607-6376-486e-9ad5-490d0032946c
relation.isAuthorOfPublication.latestForDiscovery98f055b6-738c-41c4-83c1-ffcfe6d6b33b

Files

Original bundle
Now showing 1 - 1 of 1
Thumbnail Image
Name:
Santos-2020-Predicting--month-mortality-in-inci.pdf
Size:
498.3 KB
Format:
Adobe Portable Document Format
Download

Collections

SNEF - Artigos publicados em revistas indexadas na Pubmed/Medline