Difficult management of Pediatric Acute Q Fever

Costa Figueiredo, Rafael; R. Monteiro, Diana; Rebelo, Ana Isabel; Azevedo, Ana; Freitas de Oliveira, Sara; Tavares, Sara

http://hdl.handle.net/10400.16/2517

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Authors

Costa Figueiredo, Rafael

R. Monteiro, Diana

Rebelo, Ana Isabel

Azevedo, Ana

Freitas de Oliveira, Sara

Tavares, Sara

Abstract(s)

Introduction: Q fever, a zoonosis caused by Coxiella burnetti, is relatively rare in the pediatric population. The disease is often asymptomatic or with mild clinical presentation in children. Case report: A four-year-old boy with persistent fever, severe anemia, and positive IgM for Coxiella burnetti was treated with trimethoprim-sulfamethoxazole and azithromycin, with no improvement. After polymerase chain reaction confirmation, he completed 14 days of doxycycline, with good response. After eleven months, the child remains asymptomatic. Discussion: Despite having a usually mild presentation, the severe clinical progression and lack of response to initial antibiotic therapy in this case prompt the use of doxycycline, a non-consensual drug in younger ages, with good results. New recommendations endorse the use of this drug for short periods at any age.

Keywords

Acute Q fever Doxycycline Pediatric Q fever

URI

http://hdl.handle.net/10400.16/2517

Citation

Costa Figueiredo R, R. Monteiro D, Rebelo AI, Azevedo A, Freitas de Oliveira S, Tavares S, Nascer e Crescer - Birth and Growth Medical Journal 2020;30(3): 179-182. doi:10.25753/BirthGrowthMJ.v30.i3.17089