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Impact of the COVID-19 pandemic on hospitalizations for acute coronary syndromes: a multinational study

2021Journal article Open access
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dc.contributor.authorAraiza-Garaygordobil, D
dc.contributor.authorMontalto, C
dc.contributor.authorMartinez-Amezcua, P
dc.contributor.authorCabello-Lopez, A
dc.contributor.authorGopar-Nieto, R
dc.contributor.authorAlabrese, R
dc.contributor.authorAlmaghraby, A
dc.contributor.authorCatoya-Villa, S
dc.contributor.authorChacon-Diaz, M
dc.contributor.authorKaufmann, C C
dc.contributor.authorCorbi-Pascual, M
dc.contributor.authorDeharo, P
dc.contributor.authorEl-Tahlawi, M
dc.contributor.authorElgohari-Abdelwahab, A
dc.contributor.authorGuerra, F
dc.contributor.authorJarakovic, M
dc.contributor.authorMartinez-Gomez, E
dc.contributor.authorModerato, L
dc.contributor.authorMontero, S
dc.contributor.authorMorejon-Barragan, P
dc.contributor.authorOmar, A M
dc.contributor.authorJorge-Pérez, P
dc.contributor.authorPrzybyło, P
dc.contributor.authorSelim, E
dc.contributor.authorSinan, U Y
dc.contributor.authorStratinaki, M
dc.contributor.authorTica, O
dc.contributor.authorTrêpa, Maria
dc.contributor.authorUribarri, A
dc.contributor.authorUzokov, J
dc.contributor.authorWilk, K
dc.contributor.authorCzerwińska-Jelonkiewicz, K
dc.contributor.authorSionis, A
dc.contributor.authorGierlotka, M
dc.contributor.authorLeonardi, S
dc.contributor.authorKrychtiuk, K A
dc.contributor.authorTavazzi, G
dc.date.accessioned2023-10-17T12:45:26Z
dc.date.available2023-10-17T12:45:26Z
dc.date.issued2021
dc.description.abstractBackground: COVID-19 has challenged the health system organization requiring a fast reorganization of diagnostic/therapeutic pathways for patients affected by time-dependent diseases such as acute coronary syndromes (ACS). Aim: To describe ACS hospitalizations, management, and complication rate before and after the COVID-19 pandemic was declared. Design: Ecological retrospective study. Methods: We analyzed aggregated epidemiological data of all patients > 18 years old admitted for ACS in twenty-nine hub cardiac centers from 17 Countries across 4 continents, from December 1st, 2019 to April 15th, 2020. Data from December 2018 to April 2019 were used as historical period. Results: A significant overall trend for reduction in the weekly number of ACS hospitalizations was observed (20.2%; 95% confidence interval CI [1.6, 35.4] P = 0.04). The incidence rate reached a 54% reduction during the second week of April (incidence rate ratio: 0.46, 95% CI [0.36, 0.58]) and was also significant when compared to the same months in 2019 (March and April, respectively IRR: 0.56, 95%CI [0.48, 0.67]; IRR: 0.43, 95%CI [0.32, 0.58] p < 0.001). A significant increase in door-to-balloon, door-to-needle, and total ischemic time (p <0.04 for all) in STEMI patents were reported during pandemic period. Finally, the proportion of patients with mechanical complications was higher (1.98% vs. 0.98%; P = 0.006) whereas GRACE risk score was not different. Conclusions: Our results confirm that COVID-19 pandemic was associated with a significant decrease in ACS hospitalizations rate, an increase in total ischemic time and a higher rate of mechanical complications on a international scale.pt_PT
dc.description.versioninfo:eu-repo/semantics/publishedVersionpt_PT
dc.identifier.citationAraiza-Garaygordobil D, Montalto C, Martinez-Amezcua P, et al. Impact of the COVID-19 pandemic on hospitalizations for acute coronary syndromes: a multinational study. QJM. 2021;114(9):642-647. doi:10.1093/qjmed/hcab013pt_PT
dc.identifier.doi10.1093/qjmed/hcab013pt_PT
dc.identifier.issn1460-2725
dc.identifier.issn1460-2393
dc.identifier.urihttp://hdl.handle.net/10400.16/2817
dc.language.isoengpt_PT
dc.peerreviewedyespt_PT
dc.publisherOxford Universitypt_PT
dc.relation.publisherversionhttps://watermark.silverchair.com/hcab013.pdf?token=AQECAHi208BE49Ooan9kkhW_Ercy7Dm3ZL_9Cf3qfKAc485ysgAAA1QwggNQBgkqhkiG9w0BBwagggNBMIIDPQIBADCCAzYGCSqGSIb3DQEHATAeBglghkgBZQMEAS4wEQQMtfjJX7euXpkvCetuAgEQgIIDB0BgUpdW8-yePCAYhp2gRc3W6bSUE_oaAgkox_1whRK_UZTEZbRVFnBCWq8DxiWv62UwZSauzm6SQojebNWjpex4NmlfOh4PwzQVjEXUrB12-tH0OrtWFK0xRwu8ULS4duCQXGrgSIFNSxH-V5WtkLQv7Y9vpMdWShCPeKMbbyjFayvk-ZMj2VV4IAxg1qItScFCZ4t5nU-XgsLJcJ43_b8El9hYGkcIcCT21OJ6iq6yq39Hmue6LV52WsrRC-dsJIHzYVP2rEIteB_cmpHrFluYvYOFEfydQnwccYFnGTUx0XB5LMUEZIgNffB2dszWzj2KNU71fOGe3LuRR4DTJ9_0DU2-VK0TQ-WZBsmHSyFSX_pdRW-I-hIvCFo_3MhD55TNMbyUhTVJfSyY0EI0vEvg-GHBTn5gEkrlbdU94ikgYH0Wb6oVQJlFWuuv2u45Yv30Y2Gn-edjU1AGY-5nBSUYX0aGXImePpiITS7WqziqL-aKgWjcW4NmJz65DldO7QwKW7oxeod_xyj-dbV1H5D0Jb_f8aMRh_72DINe2i7tt-zzhGdetWfl_gsDvbkZrXOxA_jgpFhlgka6SFvbjMdvRL8vpcQtekJIwlP1y_WhQu5EKMe9mHvm_WndEo6w1J8amZwiy-U9EMXot0h_4ORtCZ4MoEUbturpNZbBmwwSLBqgvHuQPGnzbw7O4iiT2hLg90kwnMc2mWBdC_PxLPFHB02Mp5qXzfNPg3e018gdC-XPog5NM109XT-mFJB5UB-bLjmAA5TxGxUgh557AT0sJQlE7RTAcc4yZ4j8rosZ76lMRjtUa6XVGvwYtoieT32M4APv9DQbDBEZu6VXHfl1gUZIwaI58tJuqAU2m7eo52j1L47vq6iT0LpkU7GoZ06GFSwvIblpE9ogZoUQWQ_F7kCsgGHTRbXiOUv9WZSqiP6QZJ2kqtdS1USDOMtqf8bn5u6AHEnXZBo8dBuYoTO5Sngw0rSELNzOseaWm7d2RCDuqMl_7dfFVgJ1TAi5KijU_63M5wwpt_PT
dc.subjectCOVID-19pt_PT
dc.titleImpact of the COVID-19 pandemic on hospitalizations for acute coronary syndromes: a multinational studypt_PT
dc.typejournal article
dspace.entity.typePublication
oaire.citation.conferencePlaceEnglandpt_PT
oaire.citation.endPage647pt_PT
oaire.citation.issue9pt_PT
oaire.citation.startPage642pt_PT
oaire.citation.titleQJM: An International Journal of Medicinept_PT
oaire.citation.volume114pt_PT
person.familyNameTrêpa
person.givenNameMaria
person.identifier.ciencia-idC31B-B4A0-9BFD
person.identifier.orcid0000-0002-7624-7750
rcaap.rightsopenAccesspt_PT
rcaap.typearticlept_PT
relation.isAuthorOfPublication3f0f0b34-eed3-4777-98d9-37221c05b4ef
relation.isAuthorOfPublication.latestForDiscovery3f0f0b34-eed3-4777-98d9-37221c05b4ef

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