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Asymmetric Thickness Intracorneal Ring Segments for Keratoconus

2020-12-16Journal article Open access
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dc.contributor.authorBaptista, Pedro Manuel
dc.contributor.authorMarques, Joao Heitor
dc.contributor.authorNeves, Miguel Mesquita
dc.contributor.authorGomes, Miguel
dc.contributor.authorOLIVEIRA, LUIS
dc.date.accessioned2021-11-16T14:06:50Z
dc.date.available2021-11-16T14:06:50Z
dc.date.issued2020-12-16
dc.description.abstractPurpose: To describe the anatomical and functional results of the implantation of asymmetric thickness intracorneal ring segments (AS-ICRS) in eyes with keratoconus and asymmetric/irregular astigmatism (type 2 - Duck - and type 3 - Snowman - phenotypes, Fernandez-Vega/Alfonso morphologic Keratoconus classification). Materials and methods: Retrospective observational study including 19 consecutive patients (21 eyes) with keratoconus who underwent manual implantation of the Keraring® Asymmetric ICRS (AS). Analysis included demographic and clinical data and Pentacam (Oculus®) measurements: topographic astigmatism; topographic flat meridian (K1), steepest meridian (K2) and the maximum keratometric point (Kmax); total root mean square (RMS) and high order RMS (HOA) aberrations and comatic Zernike coefficients (Z31;Z3-1) at 0º and 90º meridians. Results: Overall mean age was 35.3±11.7 years and median follow-up was 7.1 months (range 6-12). At the end of follow-up, a significant improvement from baseline was achieved in both UDVA (0.24±0.22; p=0.017) and CDVA (0.21±0.17; p<0.001). Regarding topographic measurements, the greatest decrease was observed in K2 (2.76±1.9D; p<0.001) and astigmatism (1.97±1.5; p<0.001). Aberrometry analysis showed a reduction of 1.27±3.2µm in the total RMS (p=0.085), 0.24±0.9µm in HOA (p=0.227) and 0.78±0.5 (p<0.001) in the 90º component of comatic aberration. The procedure effects in the CDVA, topographic and aberrometric parameters were higher in type 2 cones without statistical significance (p>0.05 in all). Conclusion: Implantation of the Keraring® Asymmetric ICRS in keratoconus with asymmetric/irregular astigmatism allowed an improvement of several clinical, topographic and aberrometric parameters, with clinical efficacy and safety, with a tendency to a greater effect in the type 2 cones.pt_PT
dc.description.versioninfo:eu-repo/semantics/publishedVersionpt_PT
dc.identifier.citationBaptista PM, Marques JH, Neves MM, Gomes M, Oliveira L. Asymmetric Thickness Intracorneal Ring Segments for Keratoconus. Clin Ophthalmol. 2020;14:4415-4421. doi:10.2147/OPTH.S283387pt_PT
dc.identifier.doi10.2147/OPTH.S283387pt_PT
dc.identifier.issn1177-5483
dc.identifier.issn1177-5467
dc.identifier.urihttp://hdl.handle.net/10400.16/2559
dc.language.isoengpt_PT
dc.peerreviewedyespt_PT
dc.publisherDove Medical Presspt_PT
dc.relation.publisherversionhttps://www.dovepress.com/asymmetric-thickness-intracorneal-ring-segments-for-keratoconus-peer-reviewed-fulltext-article-OPTHpt_PT
dc.rights.urihttp://creativecommons.org/licenses/by-nc/4.0/pt_PT
dc.subjectICRSpt_PT
dc.subjectaberrometrypt_PT
dc.subjectastigmatismpt_PT
dc.subjectasymmetricpt_PT
dc.subjectkeratoconuspt_PT
dc.titleAsymmetric Thickness Intracorneal Ring Segments for Keratoconuspt_PT
dc.typejournal article
dspace.entity.typePublication
oaire.citation.conferencePlaceNew Zealandpt_PT
oaire.citation.endPage4421pt_PT
oaire.citation.startPage4415pt_PT
oaire.citation.titleClinical Ophthalmologypt_PT
oaire.citation.volume14pt_PT
person.familyNameBaptista
person.familyNameMarques
person.familyNameNeves
person.familyNameGomes
person.familyNameOLIVEIRA
person.givenNamePedro Manuel
person.givenNameJoao Heitor
person.givenNameMiguel Mesquita
person.givenNameMiguel
person.givenNameLUIS
person.identifier.orcid0000-0001-8285-1084
person.identifier.orcid0000-0001-6487-7950
person.identifier.orcid0000-0002-3080-6035
person.identifier.orcid0000-0002-2198-7444
person.identifier.orcid0000-0001-7532-5991
rcaap.rightsopenAccesspt_PT
rcaap.typearticlept_PT
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relation.isAuthorOfPublication.latestForDiscoveryaa6920e7-d5c0-4d23-bd10-42317041c3e8

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