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Acute Ischemic Stroke in a Child Successfully Treated with Thrombolytic Therapy and Mechanical Thrombectomy

2019-02-08Journal article Open access
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dc.contributor.authorSouto Silva, R.
dc.contributor.authorRodrigues, R.
dc.contributor.authorReis Monteiro, D.
dc.contributor.authorTavares, S.
dc.contributor.authorPereira, J.
dc.contributor.authorXavier, J.
dc.contributor.authorMelo, C.
dc.contributor.authorRuano, L.
dc.date.accessioned2020-05-05T13:45:34Z
dc.date.available2020-05-05T13:45:34Z
dc.date.issued2019-02-08
dc.description.abstractAcute ischemic stroke in the pediatric population is rare but carries lasting and often lifelong morbidity. Thrombolysis and mechanical thrombectomy are mainstays of care in adults, yet there is very little evidence for these treatments in children. We present the case of a 4-year-old boy with complex congenital heart disease, admitted 30 min after sudden onset of an aphasia and right hemiplegia, scoring 14 on the Pediatric National Institutes of Health Stroke Scale (PedNIHSS). Non-contrast brain computed tomography (CT) showed no evidence of acute ischemia. CT angiogram demonstrated a thrombus in the M1 segment of the left middle cerebral artery. Intravenous recombinant tissue plasminogen activator (rTPA) was infused 3.5 h after onset of symptoms. An improvement was observed in the hour after rTPA, with a PedNIHSS score of 7. Digital subtraction angiography was performed approximately 9 h from the onset of symptoms, showing a complete left M1 occlusion. The patient underwent successful mechanical thrombectomy and was discharged with a PedNIHSS score of 2. This case emphasizes the importance of early recognition to direct children towards rapid diagnosis and hyperacute treatment.pt_PT
dc.description.versioninfo:eu-repo/semantics/publishedVersionpt_PT
dc.identifier.citationSouto Silva R, Rodrigues R, Reis Monteiro D, et al. Acute Ischemic Stroke in a Child Successfully Treated with Thrombolytic Therapy and Mechanical Thrombectomy. Case Rep Neurol. 2019;11(1):47‐52. Published 2019 Feb 8. doi:10.1159/000496535pt_PT
dc.identifier.doi10.1159/000496535pt_PT
dc.identifier.issn1662-680X
dc.identifier.urihttp://hdl.handle.net/10400.16/2361
dc.language.isoengpt_PT
dc.peerreviewedyespt_PT
dc.publisherKarger Publishers Open Accesspt_PT
dc.relation.publisherversionhttps://www.karger.com/Article/FullText/496535pt_PT
dc.rights.urihttp://creativecommons.org/licenses/by-nc/4.0/pt_PT
dc.subjectAcute ischemic strokept_PT
dc.subjectChildhoodpt_PT
dc.subjectMechanical thrombectomypt_PT
dc.subjectThrombolysispt_PT
dc.titleAcute Ischemic Stroke in a Child Successfully Treated with Thrombolytic Therapy and Mechanical Thrombectomypt_PT
dc.typejournal article
dspace.entity.typePublication
oaire.citation.conferencePlaceSwitzerlandpt_PT
oaire.citation.endPage52pt_PT
oaire.citation.issue1pt_PT
oaire.citation.startPage47pt_PT
oaire.citation.titleCase reports in neurologypt_PT
oaire.citation.volume11pt_PT
rcaap.rightsopenAccesspt_PT
rcaap.typearticlept_PT

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