Sousa, DiogoPita, SérgioOliveira, VâniaCardoso, Pedro2024-07-022024-07-022023-09Sousa D Sr, Pita S, Oliveira V, Cardoso P. Ischiopubic Ramus Resection as Treatment for Giant Cell Tumor of the Bone: Surgical Techniques in Two Clinical Cases. Cureus. 2023;15(9):e45661. doi:10.7759/cureus.456612168-8184http://hdl.handle.net/10400.16/2984Giant cell tumors (GCTs) of the ischium are rare and often diagnosed at an advanced stage. In fact, there is no defined treatment algorithm to treat this lesion. We present two case reports of Campanacci's stage three ischiopubic GCT confirmed with biopsy. They were effectively treated with excision of the ischiopubic ramus, aggressive curettage, drilling, and phenolization at the margins. The surgery was performed in a gynecological position with an approach over the ischiopubic ramus. Both cases present no recurrence (two and 10-year follow-up), and neither has a significant impact on the quality of life. A thorough plan and surgical technique were essential for the success of this intervention.enggiant cell tumor of boneischiopubic ramus resectionischiummusculoskeletal oncologyorthopedics and traumapelvic tumorsurgical procedurestreatment outcomejournal article10.7759/cureus.45661