Pereira, H.Caldeira, D.Teles, R.Costa, M.Silva, P.Ribeiro, V.Brandão, V.Martins, D.Matias, F.Pereira-Machado, F.Baptista, J.Abreu, P.Santos, R.Drummond, A.Carvalho, H.Calisto, J.Silva, J.Pipa, J.Marques, J.Sousa, P.Fernandes, R.Ferreira, R.Ramos, S.Oliveira, E.Almeida, M.2019-07-182019-07-182018-04-24BMC Cardiovasc Disord. 2018 Apr 24;18(1):691471-2261http://hdl.handle.net/10400.16/2269BACKGROUND: We aimed to evaluate the impact of thrombus aspiration (TA) during primary percutaneous coronary intervention (P-PCI) in 'real-world' settings. METHODS: We performed a retrospective study, using data from the National Registry of Interventional Cardiology (RNCI 2006-2012, Portugal) with ST-elevation myocardial infarction (STEMI) patients treated with P-PCI. The primary outcome, in-hospital mortality, was analysed through adjusted odds ratio (aOR) and 95% confidence intervals (95%CI). RESULTS: We assessed data for 9458 STEMI patients that undergone P-PCI (35% treated with TA). The risk of in-hospital mortality with TA (aOR 0.93, 95%CI:0.54-1.60) was not significantly decreased. After matching patients through the propensity score, TA reduced significantly the risk of in-hospital mortality (OR 0.58, 95%CI:0.35-0.98; 3500 patients). CONCLUSIONS: The whole cohort data does not support the routine use of TA in P-PCI, but the results of the propensity-score matched cohort suggests that the use of selective TA may improve the short-term risks of STEMI.engThrombectomyThrombus aspirationMortalityPortugalPrimary PCIAngioplastyjournal article10.1186/s12872-018-0794-4