Pina, S.Carneiro, A.Rodrigues, T.Samões, R.Taipa, R.Melo-Pires, M.Pereira, C.2015-10-262015-10-262014-02Neuroradiol J. 2014 Feb;27(1):85-901971-4009http://hdl.handle.net/10400.16/1866Glioblastoma is a malignant infiltrative glial tumor occurring most often over 50 years of age, with diverse clinical presentations. We describe a case of temporal lobe glioblastoma with a rare presentation as an acute ischemic stroke, discussing the imaging and histopathological findings, and reviewing the literature. A 77-year-old woman had sudden onset of left hemiparesis and hemihypoesthesia. The neuroradiological studies revealed an acute ischemic lesion in the right lenticulostriate arteries territory and a right anterior temporal lobe tumor, enhancing heterogeneously after contrast with enhancement of the right middle cerebral artery wall. Histopathological analysis of the resected temporal lesion revealed a glioblastoma multiforme with tumoral infiltration of the vascular wall. Glioblastoma should be considered in the etiology of acute ischemic stroke, where neuroimaging plays an important diagnostic role, enabling a more immediate therapeutic approach, with a consequent impact on survival.engglioblastoma, strokevasculopathycomputed tomographymagnetic resonance imagingjournal article10.15274/NRJ-2014-10011