Extensive skin necrosis after periprosthetic knee infection: a case that highlights the possibility of complications induced by low-molecular-weight heparin

Fonte, HélderDias Carvalho, AndreRosa, JoãoPereira, CláudiaPereira, AlexandreSousa, Ricardo2024-01-302024-01-302021-06Fonte H, Carvalho A, Rosa J, et al. Extensive skin necrosis after periprosthetic knee infection: a case that highlights the possibility of complications induced by low-molecular-weight heparin. J Bone Jt Infect. 2021;6(6):235-240. doi:10.5194/jbji-6-235-20212206-3552http://hdl.handle.net/10400.16/2904We describe a case of a patient with atrial fibrillation, anticoagulated with dabigatran, that developed severe knee skin necrosis in the setting of an acute periprosthetic knee infection, after initiating low-molecular-weight heparin. A wide range of etiology hypotheses was discussed within a multidisciplinary team. The complex approach consisted of treating the underlying infection, multiple types of soft-tissue management, and stopping enoxaparin.engExtensive skin necrosis after periprosthetic knee infection: a case that highlights the possibility of complications induced by low-molecular-weight heparinjournal article10.5194/jbji-6-235-2021