Castro-Poças, F.Araújo, T.Silva, J.Lopes, C.M Saraiva, M.2016-04-112016-04-112015-12Rev Esp Enferm Dig. 2015;107(12):759-601130-0108http://hdl.handle.net/10400.16/1923Duodenal gastrointestinal stromal tumors (GISTs) are a very rare condition. The pre-operative diagnosis can be a challenge but it is very important because GISTs have singularities that differ from other tumors and their location in the duodenum itself can have a major role in the choice of the surgical approach. We present two cases of duodenal GISTs where endoscopic ultrasound had a single role in their management, namely allowing the possibility to obtain material for immunocytochemical pre-operative diagnosis and regarding the precise relation to the papilla of Vater. The patients were operated and histological examination confirmed the diagnosis in both cases.engjournal article1130-0108/2015/107/12/759-760