Amorim, J.2012-08-282012-08-282011-12Nascer e Crescer 2011; 20(4): 294-2950872-0754http://hdl.handle.net/10400.16/1301We present the case of a 16 year-old boy with agenesis of upper lateral incisive teeth and increased interincisors spaces. The etiology of dental agenesis is unknown and the more consensual explanation is an association between genetic mutations and environmental factors. Orthodontic treatment was performed, followed by prosthodontics.porAgenesisupper lateral incisivegenetic mutationsenvironmental factorsorthodontic treatmentprosthodonticsjournal article