Carugati, ManuelaAliberti, S.Sotgiu, G.Blasi, F.Gori, A.Menendez, R.Encheva, M.Gallego, M.Leuschner, P.Ruiz-Buitrago, S.Battaglia, S.Fantini, R.Pascual-Guardia, S.Marin-Corral, J.Restrepo, M. I.Aruj, Patricia KarinaAttorri, SilviaBarimboim, EnriqueCaeiro, Juan PabloGarzón, María ICambursano, Victor HugoCeccato, AdrianChertcoff, JulioLascar, FlorenciaTulio, Fernando DiDíaz, Ariel Cordonde Vedia, LautaroGanaha, Maria CristinaLambert, SandraLopardo, GustavoLuna, Carlos MMalberti, Alessio GerardoMorcillo, NoraTartara, SilvinaPensotti, ClaudiaPereyra, BetianaScapellato, Pablo GustavoStagnaro, Juan PabloShah, SonaliLötsch, FelixThalhammer, FlorianVincent, Jean LouisAnseeuw, KurtFrancois, Camille AVan Braeckel, EvaDjimon, Marcel ZannouBashi, JulesRoger, DodoNouér, Simone AranhaChipev, PeterEncheva, MilenaMiteva, DarinaPetkova, DianaDodo, Balkissou AdamouNgahane, MbatchouHugo, BertrandShen, NingXu, Jin-fuRico, Carlos Andres BustamanteBuitrago, RicardoPaternina, Fernando Jose PereiraJean-Marie, Kayembe NtumbaCarevic, Vesna VladicJakopovic, MarkoJankovic, MatejaMatkovic, ZinkaMitrecic, IvanJacobsson, Marie-Laure BouchyChristensen, Anette BroHeitmannBødtger, Uff e ChristianMeyer, Christian NielsJensen, Andreas VestergaardBaunbæk-knudsen, GertrudPetersen, Pelle TrierAndersen, StineEl-Wahhab, Ibrahim El-Said AbdMorsy, Nesreen ElsayedShafiek, HanaaSobh, EmanBertrand, FabriceBrun-Buisson, Christiande Montmollin, EtienneFartoukh, MurielMessika, JonathanTattevin, PierreDreher, MichaelKolditz, MartinMeisinger, MatthiasPletz, Mathias WHagel, StefanRupp, JanSchaberg, TomSpielmanns, MarcSiaw-Lartey, BeatriceDimakou, KaterinaPapapetrou, DimosthenisTsigou, EvdoxiaAmpazis, DimitriosBhatia, MohitDhar, RajaD’Souza, GeorgeGarg, RajivKoul, Parvaiz AMahesh, P AJayaraj, B SNarayan, Kiran VishnuUdnur, Hirennappa BKrishnamurthy, Shashi BhaskaraGolshani, KeihanKeatings, Vera MMartin-Loeches, IgnacioMaor, YasminStrahilevitz, JacobBattaglia, SalvatoreCarrabba, MariaCeriana, PieroConfalonieri, Marcod’Arminio Monforte, AntonellaDel Prato, BrunoDe Rosa, MarinoFantini, RiccardoFiorentino, GiuseppeGammino, Maria AntoniaMenzella, FrancescoMilani, GiuseppeNava, StefanoPalmiero, GerardoPetrino, RobertaGabrielli, BarbraRossi, PaoloSorino, ClaudioSteinhilber, GundiZanforlin, AlessandroKurahashi, KiyoyasuBacha, Zeina AounUgalde, Daniel BarajasZuñiga, Omar CeballosVillegas, José FMedenica, Milicvan de Garde, E M WMihsra, Deebya RajShrestha, PoojanRidgeon, ElliottAwokola, Babatunde IsholaNwankwo, Ogonna N OOlufunlola, Adefuye BolanleOlumide, SegaoluUkwaja, Kingsley NIrfan, MuhammadMinarowski, LukaszSzymon, SkoczyńskiFroes, FelipeLeuschner, PedroMeireles, MarianaFerrão, CláudiaLeuschner, PedroNeves, JoãoRavara, Sofia Bda Beira, CovaBrocovschii, VictoriaIon, ChesovRusu, DoinaToma, CristinaChirita, DanielaBirkun, AlexeiKaluzhenina, AnnaAlmotairi, AbdullahAbdulbaqi, ZakeyaBukhary, AliEdathodu, JameelaFathy, AmalEnani, Abdullah Mushira AbdulazizMohamed, Nazik EltayebMemon, Jawed UlhadiBogdanović, NadaMilenkovic, BranislavaPesut, DragicaBorderìas, LuisGarcia, Noel Manuel BordonAlarcón, Hugo CabelloCilloniz, CatiaTorres, AntoniDiaz-Brito, VicensCasas, XavierGonzález, Alicia EncaboFernández-Almira, Maria LuisaGallego, MiguelGaspar-GarcÍa, Inmaculadadel Castillo, Juan GonzálezVictoria, Patricia JavaloyesMartínez, Elena Lasernade Molina, Rosa MaloMarcos, Pedro JMenéndez, RosarioPandoSandova, AnaAymerich, Cristina Pratdel la Torre, Alicia LacomaGarcía-Olivé, IgnasiRello, JordiMoyano, SilviaSanz, FranciscoSibila, OriolRodrigo-Troyano, AnaSolé-Violán, JordiUranga, Anevan Boven, Job FMTorra, Ester VendrellPujol, Jordi AlmirallFeldman, CharlesYum, Ho KeeFiogbe, Arnauld AttannonYangui, FerdaousBilaceroglu, SemraDalar, LeventYilmaz, UfukBogomolov, ArtemiiElahi, NaheedDhasmana, Devesh JIons, RhiannonSkeemer, JulieWoltmann, GerritHancock, CaroleHill, Adam TRudran, BanuRuiz-Buitrago, SilviaCampbell, MarionWhitaker, PaulAllen, Karen SBrito, VeronicaDietz, JessicaDysart, Claire EKellie, Susan MFranco-Sadud, Ricardo AMeier, GarnetGaga, MinaHolland, Thomas LBergin, Stephen PKheir, FayezLandmeier, MarkLois, ManuelNair, Girish BPatel, HemaliReyes, KatherineRodriguez-Cintron, WilliamSaito, ShigekiSoni, Nilam JNoda, JulioHinojosa, Cecilia ILevine, Stephanie MAngel, Luis FAnzueto, AntonioWhitlow, K ScottHipskind, JohnSukhija, KunalWunderink, Richard G.Shah, Ray DMateyo, Kondwelani John2021-11-222021-11-222020Carugati M, Aliberti S, Sotgiu G, et al. Bacterial etiology of community-acquired pneumonia in immunocompetent hospitalized patients and appropriateness of empirical treatment recommendations: an international point-prevalence study [published correction appears in Eur J Clin Microbiol Infect Dis. 2021 Sep;40(9):2051]. Eur J Clin Microbiol Infect Dis. 2020;39(8):1513-1525. doi:10.1007/s10096-020-03870-30934-97231435-4373http://hdl.handle.net/10400.16/2602An accurate knowledge of the epidemiology of community-acquired pneumonia (CAP) is key for selecting appropriate antimicrobial treatments. Very few etiological studies assessed the appropriateness of empiric guideline recommendations at a multinational level. This study aims at the following: (i) describing the bacterial etiologic distribution of CAP and (ii) assessing the appropriateness of the empirical treatment recommendations by clinical practice guidelines (CPGs) for CAP in light of the bacterial pathogens diagnosed as causative agents of CAP. Secondary analysis of the GLIMP, a point-prevalence international study which enrolled adults hospitalized with CAP in 2015. The analysis was limited to immunocompetent patients tested for bacterial CAP agents within 24 h of admission. The CAP CPGs evaluated included the following: the 2007 and 2019 American Thoracic Society/Infectious Diseases Society of America (ATS/IDSA), the European Respiratory Society (ERS), and selected country-specific CPGs. Among 2564 patients enrolled, 35.3% had an identifiable pathogen. Streptococcus pneumoniae (8.2%) was the most frequently identified pathogen, followed by Pseudomonas aeruginosa (4.1%) and Klebsiella pneumoniae (3.4%). CPGs appropriately recommend covering more than 90% of all the potential pathogens causing CAP, with the exception of patients enrolled from Germany, Pakistan, and Croatia. The 2019 ATS/IDSA CPGs appropriately recommend covering 93.6% of the cases compared with 90.3% of the ERS CPGs (p < 0.01). S. pneumoniae remains the most common pathogen in patients hospitalized with CAP. Multinational CPG recommendations for patients with CAP seem to appropriately cover the most common pathogens and should be strongly encouraged for the management of CAP patients.engAntimicrobial treatmentCommunity-acquired pneumoniaGuidelinesStreptococcus pneumoniaeBacterial etiology of community-acquired pneumonia in immunocompetent hospitalized patients and appropriateness of empirical treatment recommendations: an international point-prevalence studyjournal article10.1007/s10096-020-03870-3