Carvalho, S.Machado, S.Sampaio, R.Guedes, M.Vasconcelos, J.Semedo, D.Selores, M.2017-08-292017-08-292017-03-15Dermatol Online J. 2017 Mar 15;23(3)1087-2108http://hdl.handle.net/10400.16/2163Chronic granulomatous disease (CGD) is a primaryimmunodeficiency disorder that affects the phagocyticcells of the innate immune system. It is characterizedby recurrent or persistent infections with granulomaformation. Lupus-like lesions have been reported incarriers of CGD and less frequently, in patients withCGD. Immunological study in these patients areusually negative. We describe the case of an 8-yearoldboy with CGD who developed chronic and acutecutaneous lupus erythematous with angular cheilitis,oral ulcers, Raynaud phenomenon, and positiveserologies for antinuclear, anticentromere, and anti-Saccharomyces cerevisiae antibodies.engprimary immunodeficiencychronic granulomatous diseaselupus erythematousjournal article