Palha Ribeiro, AntonioGonçalves, AnaMateus, CarolinaMexêdo, Carlos2024-06-182024-06-182023-05Palha Ribeiro A, Gonçalves A, Mateus C, Mexêdo C. Beyond the Usual: Pantoprazole-Induced Anaphylaxis During Peribulbar Anesthesia. Cureus. 2023;15(5):e38738. doi:10.7759/cureus.387382168-8184http://hdl.handle.net/10400.16/2966Proton-pump inhibitors (PPIs) are one of the most prescribed drugs in the world. Although they are remarkably safe, with minimal adverse effects, it has rarely been reported as a cause of anaphylaxis. Hence, we report the case of a 69-year-old patient who experienced intravenous pantoprazole-induced anaphylaxis during peribulbar block anesthesia for mechanical vitrectomyengadrenalineanaphylaxispantoprazoleperibulbar anesthesiaproton-pump inhibitorjournal article10.7759/cureus.38738