Browsing by Author "Costa, C."
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- Pneumonia com pneumatocelos: caso clínicoPublication . Moreira, E.; Machado, L.; Costa, C.; Xavier, C.; Quintal, I.; Cunha, J.; Garrido, C.Os pneumatocelos são cistos preenchidos por ar que se desenvolvem no parênquima pulmonar geralmente no decurso de uma pneumonia. Embora vários agentes possam estar implicados, a etiologia mais frequente é a pneumonia estafilocócica. O tratamento é o da pneumonia de base com antibioterapia adequada. O seu curso natural é a resolução lenta sem sequelas. Os autores apresentam um caso clínico de uma lactente de um mês com pneumonia com pneumatocelos, sem isolamento de agente e com evolução favorável. ABSTRACT Pneumatoceles are air-filled cysts that develop in the pulmonary parenchyma usually during pneumonia. Staphylococcus aureus is the most frequent agent. Treatment of the underlying pneumonia with antibiotics is the first line of therapy. The natural course is slow resolution with no further squeal. The authors report a case of pneumonia with pneumatocele in a one month old infant without identification of the agent with a complete resolution.
- Seemingly Harmless Differentiated Thyroid Carcinoma Presenting as Bone MetastasisPublication . Magalhães, D.; Costa, C.; Furtado, I.; Matos, M.; Santos, A.; Duarte, H.; Afonso, M.; Lobo, J.; Torres, I.Thyroid carcinoma is the most common endocrine neoplasia. Differentiated thyroid carcinomas (DTCs) represent the majority of cases, which usually follow an indolent clinical course with low mortality rates. The authors describe two cases of well DTC without classic histological poor prognosis features, presenting as extensive and unresectable osteolytic bone metastases. DTCs are considered harmless tumours, due to their benign and silent behaviour. The authors want to underline the importance of clinical awareness during follow-up in cases of DTC, which can be aggressive in presentation and behaviour. Timely identification and diagnosis of these tumours are essential for prompt treatment initiation and improvement of overall survival.
- The Portuguese Severe Asthma Registry: Development, Features, and Data Sharing PoliciesPublication . Sá-Sousa, A.; Fonseca, J.; Pereira, A.; Ferreira, A.; Arrobas, A.; Mendes, A.; Drummond, M.; Videira, W.; Costa, T.; Farinha, P.; Soares, J.; Rocha, P.; Todo-Bom, A.; Sokolova, A.; Costa, A.; Fernandes, B.; Chaves Loureiro, C.; Longo, C.; Pardal, C.; Costa, C.; Cruz, C.; Loureiro, C.; Lopes, C.; Mesquita, D.; Faria, E.; Magalhães, E.; Menezes, F.; Todo-Bom, F.; Carvalho, F.; Regateiro, F.; Falcao, H.; Fernandes, I.; Gaspar-Marques, J.; Viana, J.; Ferreira, J.; Silva, J.; Simão, L.; Almeida, L.; Fernandes, L.; Ferreira, L.; van Zeller, M.; Quaresma, M.; Castanho, M.; André, N.; Cortesão, N.; Leiria-Pinto, P.; Pinto, P.; Rosa, P.; Carreiro-Martins, P.; Gerardo, R.; Silva, R.; Lucas, S.; Almeida, T.; Calvo, T.The Portuguese Severe Asthma Registry (Registo de Asma Grave Portugal, RAG) was developed by an open collaborative network of asthma specialists. RAG collects data from adults and pediatric severe asthma patients that despite treatment optimization and adequate management of comorbidities require step 4/5 treatment according to GINA recommendations. In this paper, we describe the development and implementation of RAG, its features, and data sharing policies. The contents and structure of RAG were defined in a multistep consensus process. A pilot version was pretested and iteratively improved. The selection of data elements for RAG considered other severe asthma registries, aiming at characterizing the patient's clinical status whilst avoiding overloading the standard workflow of the clinical appointment. Features of RAG include automatic assessment of eligibility, easy data input, and exportable data in natural language that can be pasted directly in patients' electronic health record and security features to enable data sharing (among researchers and with other international databases) without compromising patients' confidentiality. RAG is a national web-based disease registry of severe asthma patients, available at asmagrave.pt. It allows prospective clinical data collection, promotes standardized care and collaborative clinical research, and may contribute to inform evidence-based healthcare policies for severe asthma.