Browsing by Author "Leite, L."
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- Caso hematológico: hemorragia tardia pós adeno-amigdalectomiaPublication . Salgado, M.; Costa, E.; Campos, F.; Leite, L.; Freitas, I.; Barbot, J.The authors present the clinical case of a six years old child followed by Pediatric Hematology because of anemia detected after a late hemorrhage following adenotonsillectomy, debating the differential diagnosis and management.
- Portuguese Position Paper on the Use of Biosimilars in PsoriasisPublication . Torres, T.; Ferreira, A.; Ferreira, P.; Henriques, M.; Leite, L.; Magina, S.; Marques-Pinto, G.; Oliveira, H.; Sousa-Basto, A.; Tavares-Bello, R.; Varela, P.; Massa, A.; Selores, M.; Filipe, P.
- Rheumatic hand's clinical, functional and imagiological correlations following metacarpophalangeal joint silicone arthroplastyPublication . Figueiredo, S.; Pereira, A.; Silva, M.; Leite, L.; Costa, G.; Silva, C.Objective: Evaluation of rheumatoid hand-associated metacarpophalangeal joint silicone arthroplasty most often relies on functional scores alone. This study aimed to understand the correlation between perceived and observed function, strength, and alignment. Methods: Cross-sectional study including all 11 women (15 hands) submitted to second to fifth metacarpophalangeal joint arthroplasty due to rheumatoid arthritis involvement for a time period of seven years. Measurements relied on the Michigan Hand Outcomes Questionnaire, Lafayette Purdue Pegboard, pinch and grip strength, and analysis of a lateral "OK-sign" X-ray view. Correlation analysis used Spearman's coefficient, assuming statistical significance for p-values < 0.05. Results: Objective function was strongly correlated with all other variables (p < 0.05), while perceived function failed to correlate with articular alignment in both measurements (p = 0.240 and p = 0.354). Strength and alignment were also strongly correlated (p < 0.05). Conclusions: Most measurements strongly correlate with each other, with emphasis on objective dexterity measurement.
- Ustekinumab in Real-Life Practice: Experience in 116 Patients with Moderate-To-Severe PsoriasisPublication . Raposo, I.; Bettencourt, A.; Leite, L.; Selores, M.; T, TorresUstekinumab is a monoclonal antibody directed against the p40 subunit common to both IL-12 and IL-23 cytokines. Although the evidence of ustekinumab efficacy and safety in clinical trials is extensively recognized, data on its use in clinical practice is limited. Our objective is to report on the real-life experience of two Portuguese dermatology departments with ustekinumab in patients with moderate to severe psoriasis, and to identify the clinical characteristics associated with a weaker clinical response.