Browsing by Issue Date, starting with "2001-09"
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- Neoplasia renal con extensión a la vena cavaPublication . Barradas, D.; Araújo, D.; Pimenta, A.La neoplasia renal con extensión a la vena cava es relativamente rara (4-10%). Cualquiera que sea la terapia coadjuvante (radioterapia, hormonal, quimioterapia e inmunoterapia), la exéresis completa del trombo tumoral de la vena cava continúa siendo la mejor forma de tratamiento. El valor pronóstico de la extensión cefálica de un trombo tumoral en la vena cava inferior en enfermos con carcinoma de células renales es controvertido. Es posible conseguir una larga supervivencia después del tratamiento quirúrgico en enfermos con carcinoma de células renales localizado (supervivencia de 50% en 5 años). Los autores describen un caso de carcinoma de células renales con extensión a la vena cava en un enfermo del sexo masculino, de 70 años de edad. El enfermo presentaba una historia de lumbalgia derecha y edema del miembro inferior homolateral. La resonancia magnética demostró la presencia y el nivel del trombo tumoral. El enfermo fue sometido a nefrectomía radical derecha y exéresis completa del trombo tumoral de la vena cava. Renal cancer with vena cava tumour thrombus is relatively rare (4 to 10%). Because of the poor results obtained with any kind of alternative therapy (e.g. radiation, hormonal, chemotherapy and immunotherapy) operation with complete removal of the vena cava tumour thrombus continues to be the better method of treatment. The prognostic significance of the cephalic extent of an inferior vena caval tumor thrombus associated with renal cell carcinoma is controversial. Long-term survival after surgical treatment is possible in patients with localized renal cell carcinoma (survival 50% at five years). The authors report a case of vena caval extension of renal cell carcinoma in a 70-years-old man. The patient presented with a history of right lombar pain and pedal edema. Magnetic Ressonance demonstrated the presence and the level of tumoral thrombus. The patient was submitted to a radical nefrectomy and complete removal of tumor thrombus from vena caval.
- Dysgenetic male pseudohermaphroditismPublication . Proença, E.; Freitas, S.; Fonseca, M.; Figueiredo, S.; Rodrigues, C.Acta Med Port. 2001 Sep-Dec;14(5-6):511-4. [Dysgenetic male pseudohermaphroditism] [Article in Portuguese] Proença E, Freitas S, Fonseca M, Figueiredo S, Rodrigues C. Serviço de Cirurgia Pediátrica, Hospital Maria Pia, Porto. Abstract Dysgenetic male pseudohermaphroditism is the result of a defect of testis development that encompasses a large clinical heterogeneity. It is characterized by bilateral dysgenetic testis, absence of mullerian regression, ambiguous genitalia and/or stigmata of Turner's syndrome in the majority of the cases. Typically, these individuals have either a 46,XY or 45,X/46,XY karyotype. The authors present four cases of dysgenetic male psudohermaphroditism, with ages of diagnosis between 1 month and 17 years old. The first had a male phenotype with stigmata of Turner's syndrome and the others ambiguous genitalia. Two patients were 45,X/46,XY and 45X/47,XYY mosaics and the other two were 46,XY. Gonadal karyotyping showed mosaicism (45,X/46,XY) in all four cases. In the first case was programed orquidectomy; all the others assigned a male gender, with regular follow-up until the puberty. PMID: 11878163 [PubMed - indexed for MEDLINE]
- Cutaneous necrobiotic xanthogranuloma (NXG)--successfully treated with low dose chlorambucil.Publication . Machado, S.; Alves, R.; Lima, M.; Leal, I.; Massa, A.Eur J Dermatol. 2001 Sep-Oct;11(5):458-62. Cutaneous necrobiotic xanthogranuloma (NXG)--successfully treated with low dose chlorambucil. Machado S, Alves R, Lima M, Leal I, Massa A. SourceService of Dermatology, Hospital Geral Santo António, Rua D. Manuel II, Edifício ex: Cicap, 4099-001 Porto, Portugal. basleite@esoterica.pt Abstract We report a case of necrobiotic xanthogranuloma in a 51 year-old white male patient presenting with a 6-year history of multiple indurated violaceous nodules and plaques involving the eyelids, trunk and extremities. He had an associated paraproteinemia (Ig G lambda), elevated sedimentation rate, cryoglobulinemia and hypocomplementemia. No extracutaneous involvement was detected. He was successfully treated with chlorambucil (2 mg/d for 7 months), leading to disappearance of all skin lesions.