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Moura de Azevedo, Sofia

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  • A Rare Case of Mediastinal Mass: Thymoma and Thymic Tumor
    Publication . Moura De Azevedo, Sofia; Baptista, Patrícia; Pichel, Rita C; Dias, Rita R; Bertão, Manuela
    Thymomas and thymic carcinomas are rare mediastinal neoplasms arising from thymic epithelial cells, and the presence of synchronous or metachronous primary thymic neoplasms in a single patient is an extremely rare event. Thymoma patients appear to have an inherent predisposition toward developing additional neoplasms. This additionally presents a diagnostic challenge, revealing the importance of multidisciplinary expertise to the management of these patients. This is a case report of a patient with a thymoma and thymic carcinoma, submitted to surgical resection and postoperative radiotherapy
  • Case Report and Literature Review of Cardiac Amyloidosis: A Not-So-Rare Cause of Heart Failure
    Publication . Baptista, Patrícia; Moura De Azevedo, Sofia; Alexandre, André; Dias-Frias, André
    Restrictive cardiomyopathy secondary to cardiac amyloidosis is an underdiagnosed cause of heart failure and it is associated with significant morbidity and mortality. The most common types of amyloidosis are light chain amyloidosis, transthyretin amyloidosis and secondary amyloidosis. We report the case of a 84-year-old man that presented with new onset signs and symptoms of heart failure. Multimodality imaging with echocardiogram and bone tracer cardiac scintigraphy along with biomarkers, monoclonal proteins analysis and genetic test allowed to diagnosed a wild-type transthyretin amyloidosis. We discuss the clinical and diagnostic features and review the current literature about cardiac amyloidosis. This paper aims to increase clinicians' awareness of cardiac amyloidosis to promptly recognize, diagnose and treat it.