Repository logo
 
Publication

Positive blood culture and neonatal sepsis – A five-year study

2022-03Journal article Open access
Simple item page
dc.contributor.authorFerreira, Adriana
dc.contributor.authorSousa, Eulália
dc.contributor.authorFreitas, Joaquim
dc.contributor.authorVieira, Mariana
dc.contributor.authorMiranda, Filipa
dc.contributor.authorSilva, Francisco
dc.date.accessioned2023-02-02T13:13:45Z
dc.date.available2023-02-02T13:13:45Z
dc.date.issued2022-03
dc.description.abstractIntroduction: Neonatal sepsis remains a major cause of morbidity and mortality in pediatric age. Since the predominant causative microorganisms vary between regions and over time, it is crucial to know the local epidemiology. The aim of this study was to characterize patients with positive blood culture and clinical presentation of sepsis admitted to a Neonatology Unit and identify possible risk factors and implicated microorganisms and respective antimicrobial susceptibility patterns. Methods: This was a retrospective descriptive study of clinical data of patients admitted to the Neonatology Unit of a level II hospital with positive blood culture and clinical presentation of sepsis over five years (2014-2018). Results: Seventy-three culture-proven sepsis cases were identified, 51 (69.9%) of which corresponded to low-birth-weight neonates and 52 (71.2%) to preterm newborns. Most cases (60; 82.2%) concerned late-onset sepsis. The most frequent microorganisms identified were coagulase-negative Staphylococcus (55; 75.3%), mainly associated with late-onset sepsis. Group B Streptococcus and Escherichia coli were the most common microorganisms isolated in early-onset sepsis. No cases of methicillin-resistant Staphylococcus aureus were identified. Coagulase-negative Staphylococcus presented high resistance rates to beta-lactam antibiotics. Conclusions: The results retrieved from this study document the local epidemiology of neonatal sepsis and show a high frequency of late-onset sepsis associated with nosocomial pathogens. Coagulase-negative Staphylococcus spp. are resistant to the most commonly used antibiotics, with these cases requiring the use of vancomycin. It is crucial to implement effective guidelines to control and prevent nosocomial infections and reduce the incidence, morbidity, and mortality of neonatal sepsis, as well as the need for broad-spectrum antibiotics.pt_PT
dc.description.versioninfo:eu-repo/semantics/publishedVersionpt_PT
dc.identifier.citationNascer e Crescer - Birth and Growth Medical Journal 2022;31(2):106-114. doi:10.25753/BirthGrowthMJ.v31.i2.23899pt_PT
dc.identifier.doihttps://doi.org/10.25753/BirthGrowthMJ.v31.i2.23899pt_PT
dc.identifier.eissn2183-9417
dc.identifier.urihttp://hdl.handle.net/10400.16/2771
dc.language.isoengpt_PT
dc.peerreviewedyespt_PT
dc.publisherCentro Hospitalar Universitário do Portopt_PT
dc.rights.urihttp://creativecommons.org/licenses/by-nc/4.0/pt_PT
dc.subjectantimicrobial susceptibilitypt_PT
dc.subjectblood culturept_PT
dc.subjectnewbornpt_PT
dc.subjectsepsispt_PT
dc.titlePositive blood culture and neonatal sepsis – A five-year studypt_PT
dc.title.alternativeHemocultura positiva e sépsis neonatal – Casuística de cinco anospt_PT
dc.typejournal article
dspace.entity.typePublication
oaire.citation.conferencePlacePortopt_PT
oaire.citation.endPage114pt_PT
oaire.citation.issue2pt_PT
oaire.citation.startPage106pt_PT
oaire.citation.titleNascer e Crescer - Birth and Growth Medical Journalpt_PT
oaire.citation.volume31pt_PT
person.familyNameFerreira
person.familyNameSousa
person.familyNameFreitas
person.familyNameCatanho da Silva Vieira
person.familyNamePinto de Barros Miranda
person.familyNameEspincho Duarte Pereira da Silva
person.givenNameAdriana
person.givenNameEulália
person.givenNameJoaquim
person.givenNameMariana
person.givenNameFilipa
person.givenNameFrancisco Manuel
person.identifier.ciencia-idA915-E451-9EE1
person.identifier.ciencia-id2D12-4B58-1FED
person.identifier.ciencia-idF411-7F9E-CC14
person.identifier.orcid0000-0003-4751-1839
person.identifier.orcid0000-0001-8292-6971
person.identifier.orcid0000-0002-2004-5068
person.identifier.orcid0000-0001-5928-4237
rcaap.rightsopenAccesspt_PT
rcaap.typearticlept_PT
relation.isAuthorOfPublicationc1da2874-34b0-41e1-b3d8-4449f886b5c6
relation.isAuthorOfPublication7868fa05-4ecc-4aa8-9898-fca7dd385250
relation.isAuthorOfPublication427862cb-7283-43ee-9a47-a1ee6166ec34
relation.isAuthorOfPublication6fd460bc-b22a-4489-81a4-e62605ff5c85
relation.isAuthorOfPublication4e74a664-6ee2-4f96-8e36-941423cd1f10
relation.isAuthorOfPublicationeeccb2ea-f5f3-4aa1-9deb-e7a5de8aac18
relation.isAuthorOfPublication.latestForDiscoveryc1da2874-34b0-41e1-b3d8-4449f886b5c6

Files

Original bundle
Now showing 1 - 1 of 1
Thumbnail Image
Name:
23899-Article Text-114129-1-10-20220630.pdf
Size:
304.98 KB
Format:
Adobe Portable Document Format
Download
License bundle
Now showing 1 - 1 of 1
No Thumbnail Available
Name:
license.txt
Size:
1.35 KB
Format:
Item-specific license agreed upon to submission
Description:
Download

Collections

RN&C: Ano de 2022